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Procedure price report · Laboratory - Chemistry and Hematology

Blood test for total protein S

CPT 85305the billing code this page is about

A blood test measuring the total amount of protein S, a natural clot-limiting protein, in the blood. Billed once per test.

Hospitals typically charge $79 cash for this outpatient procedure — the median across 2,774 hospitals that filed a usable cash price; the average of the middle 60% is $90. Most fall between $29 and $189 (20th–80th percentile).

Hospitals
2,774
States
50
Filings dated
Aug 2022 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 2,774 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$18$36$79$163$286

The most expensive tenth of hospitals charges at least 16× what the cheapest tenth charges ($18 vs $286).

How the prices are spread

$13 – $18: 151 hospitals$13$18 – $26: 194 hospitals$26 – $38: 262 hospitals$26$38 – $54: 236 hospitals$54 – $78: 406 hospitals$54$78 – $112: 333 hospitals$112 – $161: 335 hospitals$112$161 – $230: 316 hospitals$230 – $331: 184 hospitals$230$331 – $474: 84 hospitals$331median $79price bands are equal on a log scale
Hospitals per price band (2,501 of 2,774 — the bands cover the 5th to 95th percentile)
FromToHospitals
$13$18151
$18$26194
$26$38262
$38$54236
$54$78406
$78$112333
$112$161335
$161$230316
$230$331184
$331$47484

By state

The median cash price in each state, against the national median of $79.

Alaska: median $134 across 17 hospitalsAK$134Maine: median $52 across 18 hospitalsME$52Vermont: 9 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: median $86 across 22 hospitalsNH$86Washington: median $75 across 60 hospitalsWA$75Idaho: median $59 across 19 hospitalsID$59Montana: median $91 across 15 hospitalsMT$91North Dakota: median $78 across 22 hospitalsND$78Minnesota: median $103 across 69 hospitalsMN$103Illinois: median $115 across 133 hospitalsIL$115Wisconsin: median $123 across 95 hospitalsWI$123Michigan: median $34 across 57 hospitalsMI$34New York: median $42 across 94 hospitalsNY$42Massachusetts: median $95 across 49 hospitalsMA$95Oregon: median $71 across 28 hospitalsOR$71Nevada: median $82 across 20 hospitalsNV$82Wyoming: median $50 across 12 hospitalsWY$50South Dakota: median $228 across 19 hospitalsSD$228Iowa: median $79 across 68 hospitalsIA$79Indiana: median $93 across 93 hospitalsIN$93Ohio: median $103 across 134 hospitalsOH$103Pennsylvania: median $72 across 102 hospitalsPA$72New Jersey: median $13 across 56 hospitalsNJ$13Connecticut: median $43 across 20 hospitalsCT$43Rhode Island: 9 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $63 across 117 hospitalsCA$63Utah: median $76 across 40 hospitalsUT$76Colorado: median $80 across 59 hospitalsCO$80Nebraska: median $204 across 55 hospitalsNE$204Missouri: median $125 across 67 hospitalsMO$125Kentucky: median $71 across 64 hospitalsKY$71West Virginia: median $90 across 34 hospitalsWV$90Virginia: median $100 across 71 hospitalsVA$100Maryland: median $163 across 37 hospitalsMD$163Delaware: 7 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $116 across 36 hospitalsAZ$116New Mexico: median $148 across 10 hospitalsNM$148Kansas: median $85 across 61 hospitalsKS$85Arkansas: median $76 across 27 hospitalsAR$76Tennessee: median $73 across 77 hospitalsTN$73North Carolina: median $59 across 70 hospitalsNC$59South Carolina: median $128 across 49 hospitalsSC$128Oklahoma: median $99 across 62 hospitalsOK$99Louisiana: median $40 across 48 hospitalsLA$40Mississippi: median $80 across 49 hospitalsMS$80Alabama: median $73 across 41 hospitalsAL$73Georgia: median $88 across 97 hospitalsGA$88Hawaii: median $78 across 15 hospitalsHI$78Texas: median $101 across 201 hospitalsTX$101Florida: median $24 across 140 hospitalsFL$24
Cash price by state, most expensive first. National median $79. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
South Dakota SD19$228+189%$74 – $424
Nebraska NE55$204+159%$62 – $272
Maryland MD37$163+107%$108 – $192
New Mexico NM10$148+88%$37 – $267
Alaska AK17$134+70%$57 – $257
South Carolina SC49$128+62%$68 – $222
Missouri MO67$125+59%$74 – $243
Wisconsin WI95$123+57%$58 – $183
Arizona AZ36$116+48%$26 – $155
Illinois IL133$115+46%$60 – $261
Ohio OH134$103+31%$40 – $180
Minnesota MN69$103+31%$55 – $240
Texas TX201$101+28%$37 – $386
Virginia VA71$100+26%$43 – $179
Oklahoma OK62$99+26%$43 – $215
Massachusetts MA49$95+21%$31 – $216
Indiana IN93$93+18%$28 – $245
Montana MT15$91+15%$33 – $129
West Virginia WV34$90+14%$41 – $157
Georgia GA97$88+12%$53 – $215
New Hampshire NH22$86+10%$36 – $281
Kansas KS61$85+8%$43 – $177
Nevada NV20$82+4%$24 – $203
Colorado CO59$80+2%$27 – $186
Mississippi MS49$80+2%$35 – $141
Iowa IA68$790%$33 – $157
Hawaii HI15$78−1%$57 – $154
North Dakota ND22$78−2%$20 – $150
Utah UT40$76−3%$65 – $129
Arkansas AR27$76−4%$28 – $158
Washington WA60$75−4%$40 – $147
Tennessee TN77$73−7%$35 – $160
Alabama AL41$73−7%$26 – $173
Pennsylvania PA102$72−9%$13 – $193
Kentucky KY64$71−9%$35 – $189
Oregon OR28$71−10%$17 – $143
California CA117$63−20%$15 – $108
Idaho ID19$59−26%$29 – $76
North Carolina NC70$59−26%$19 – $198
Maine ME18$52−34%$42 – $87
Wyoming WY12$50−37%$37 – $149
Connecticut CT20$43−46%$19 – $70
New York NY94$42−47%$12 – $140
Louisiana LA48$40−49%$20 – $105
Michigan MI57$34−57%$16 – $183
Florida FL140$24−69%$10 – $56
New Jersey NJ56$13−83%$13 – $66
Rhode Island RI9not enough hospitals filed a usable price
Vermont VT9not enough hospitals filed a usable price
Delaware DE7not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $79.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care2,017$74$27 – $185
Children’s43$78$30 – $197
Critical access704$94$41 – $198
Ownership
For-profit407$101$31 – $376
Government483$82$33 – $186
Non-profit1,874$76$29 – $179
System affiliation
Part of a system2,273$80$29 – $190
Independent501$76$33 – $186

Cash price vs list price

Median list price (chargemaster)$130
Median cash price$79
Cash as a share of list, median hospital65%

At the typical hospital, asking for the cash price cuts the list price by about 35%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

1,915 hospitals filed a usable inpatient cash price for this code. The median is $80 and the average of the middle 60% is $92; most fall between $33 and $183.

Cash price percentiles, inpatient, across 1,915 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$22$40$80$163$264

The most expensive tenth of hospitals charges at least 12× what the cheapest tenth charges ($22 vs $264).

Of the 2,109 hospitals that filed this code inpatient, 1,915 gave a usable cash price; 101 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 93 a list price only.

How complete is this

2,774 of the 3,956 hospitals with a price file in our corpus (70%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 3,026 hospitals that filed this code at all gave us
Usable cash price — counted2,774
Cash price carrying a plausibility flag — shown on the compare tool, excluded here138
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded0
An estimate rather than a filed cash price — excluded1
A list price only, no cash figure — excluded113
Hospitals that filed this code3,026

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between July 20, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Laboratory - Chemistry and Hematology family.

Hospitals file this code under descriptions such as Hc Clot Inhib Protein S,Total.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Blood test for total protein S (CPT 85305) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-85305-blood-test-for-total-protein-s