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Procedure price report · Laboratory - Chemistry and Hematology

Blood test for protein C activity

CPT 85303the billing code this page is about

A blood test that measures how well protein C, a natural clot-limiting protein, is working. Billed once per test.

Hospitals typically charge $103 cash for this outpatient procedure — the median across 3,193 hospitals that filed a usable cash price; the average of the middle 60% is $108. Most fall between $35 and $210 (20th–80th percentile).

Hospitals
3,193
States
50
Filings dated
Dec 2022 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 3,193 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$22$42$103$184$300

The most expensive tenth of hospitals charges at least 14× what the cheapest tenth charges ($22 vs $300).

How the prices are spread

$15 – $21: 168 hospitals$15$21 – $30: 217 hospitals$30 – $43: 280 hospitals$30$43 – $60: 227 hospitals$60 – $85: 307 hospitals$60$85 – $120: 478 hospitals$120 – $169: 425 hospitals$120$169 – $239: 453 hospitals$239 – $337: 232 hospitals$239$337 – $476: 96 hospitals$337median $103price bands are equal on a log scale
Hospitals per price band (2,883 of 3,193 — the bands cover the 5th to 95th percentile)
FromToHospitals
$15$21168
$21$30217
$30$43280
$43$60227
$60$85307
$85$120478
$120$169425
$169$239453
$239$337232
$337$47696

By state

The median cash price in each state, against the national median of $103.

Alaska: median $123 across 18 hospitalsAK$123Maine: median $80 across 28 hospitalsME$80Vermont: median $213 across 14 hospitalsVT$213New Hampshire: median $105 across 25 hospitalsNH$105Washington: median $109 across 73 hospitalsWA$109Idaho: median $72 across 22 hospitalsID$72Montana: median $128 across 27 hospitalsMT$128North Dakota: median $83 across 29 hospitalsND$83Minnesota: median $127 across 101 hospitalsMN$127Illinois: median $150 across 136 hospitalsIL$150Wisconsin: median $168 across 103 hospitalsWI$168Michigan: median $40 across 94 hospitalsMI$40New York: median $52 across 104 hospitalsNY$52Massachusetts: median $107 across 52 hospitalsMA$107Oregon: median $84 across 47 hospitalsOR$84Nevada: median $81 across 20 hospitalsNV$81Wyoming: median $140 across 15 hospitalsWY$140South Dakota: median $266 across 27 hospitalsSD$266Iowa: median $110 across 83 hospitalsIA$110Indiana: median $97 across 97 hospitalsIN$97Ohio: median $83 across 139 hospitalsOH$83Pennsylvania: median $97 across 120 hospitalsPA$97New Jersey: median $16 across 57 hospitalsNJ$16Connecticut: median $70 across 21 hospitalsCT$70Rhode Island: median $102 across 10 hospitalsRI$102California: median $88 across 144 hospitalsCA$88Utah: median $105 across 39 hospitalsUT$105Colorado: median $131 across 70 hospitalsCO$131Nebraska: median $176 across 74 hospitalsNE$176Missouri: median $126 across 73 hospitalsMO$126Kentucky: median $117 across 69 hospitalsKY$117West Virginia: median $55 across 40 hospitalsWV$55Virginia: median $149 across 73 hospitalsVA$149Maryland: median $163 across 40 hospitalsMD$163Delaware: 7 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $130 across 39 hospitalsAZ$130New Mexico: median $152 across 26 hospitalsNM$152Kansas: median $132 across 83 hospitalsKS$132Arkansas: median $59 across 38 hospitalsAR$59Tennessee: median $73 across 78 hospitalsTN$73North Carolina: median $99 across 85 hospitalsNC$99South Carolina: median $203 across 52 hospitalsSC$203Oklahoma: median $92 across 64 hospitalsOK$92Louisiana: median $85 across 49 hospitalsLA$85Mississippi: median $57 across 53 hospitalsMS$57Alabama: median $74 across 42 hospitalsAL$74Georgia: median $135 across 103 hospitalsGA$135Hawaii: median $103 across 18 hospitalsHI$103Texas: median $173 across 230 hospitalsTX$173Florida: median $27 across 142 hospitalsFL$27
Cash price by state, most expensive first. National median $103. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
South Dakota SD27$266+159%$130 – $365
Vermont VT14$213+107%$84 – $275
South Carolina SC52$203+97%$53 – $320
Nebraska NE74$176+71%$75 – $253
Texas TX230$173+68%$41 – $387
Wisconsin WI103$168+63%$59 – $185
Maryland MD40$163+58%$120 – $195
New Mexico NM26$152+48%$90 – $274
Illinois IL136$150+46%$86 – $344
Virginia VA73$149+44%$24 – $278
Wyoming WY15$140+36%$27 – $174
Georgia GA103$135+31%$50 – $228
Kansas KS83$132+28%$73 – $210
Colorado CO70$131+27%$68 – $239
Arizona AZ39$130+27%$23 – $242
Montana MT27$128+24%$39 – $218
Minnesota MN101$127+23%$45 – $212
Missouri MO73$126+22%$78 – $190
Alaska AK18$123+19%$37 – $276
Kentucky KY69$117+14%$42 – $186
Iowa IA83$110+6%$38 – $158
Washington WA73$109+6%$63 – $185
Massachusetts MA52$107+4%$46 – $262
Utah UT39$105+2%$93 – $124
New Hampshire NH25$105+2%$44 – $216
Hawaii HI18$1030%$86 – $178
Rhode Island RI10$102−1%$44 – $120
North Carolina NC85$99−4%$31 – $214
Pennsylvania PA120$97−6%$21 – $262
Indiana IN97$97−6%$42 – $199
Oklahoma OK64$92−11%$42 – $163
California CA144$88−15%$17 – $116
Louisiana LA49$85−18%$31 – $155
Oregon OR47$84−18%$42 – $188
North Dakota ND29$83−19%$25 – $112
Ohio OH139$83−19%$38 – $152
Nevada NV20$81−21%$20 – $214
Maine ME28$80−22%$38 – $116
Alabama AL42$74−28%$32 – $186
Tennessee TN78$73−29%$24 – $185
Idaho ID22$72−30%$35 – $82
Connecticut CT21$70−32%$57 – $115
Arkansas AR38$59−43%$11 – $157
Mississippi MS53$57−45%$22 – $165
West Virginia WV40$55−47%$31 – $154
New York NY104$52−49%$19 – $259
Michigan MI94$40−61%$27 – $75
Florida FL142$27−74%$15 – $109
New Jersey NJ57$16−85%$14 – $71
Delaware DE7not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $103.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care2,233$94$30 – $206
Children’s62$116$48 – $250
Critical access888$117$52 – $215
Ownership
For-profit442$116$37 – $341
Government585$110$40 – $218
Non-profit2,156$99$33 – $193
System affiliation
Part of a system2,602$104$33 – $211
Independent591$103$42 – $210

Cash price vs list price

Median list price (chargemaster)$164
Median cash price$103
Cash as a share of list, median hospital65%

At the typical hospital, asking for the cash price cuts the list price by about 35%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

2,150 hospitals filed a usable inpatient cash price for this code. The median is $102 and the average of the middle 60% is $106; most fall between $38 and $201.

Cash price percentiles, inpatient, across 2,150 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$24$44$102$180$275

The most expensive tenth of hospitals charges at least 11× what the cheapest tenth charges ($24 vs $275).

Of the 2,367 hospitals that filed this code inpatient, 2,150 gave a usable cash price; 112 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 105 a list price only.

How complete is this

3,193 of the 3,956 hospitals with a price file in our corpus (81%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 3,471 hospitals that filed this code at all gave us
Usable cash price — counted3,193
Cash price carrying a plausibility flag — shown on the compare tool, excluded here152
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded0
An estimate rather than a filed cash price — excluded1
A list price only, no cash figure — excluded125
Hospitals that filed this code3,471

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between July 20, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Laboratory - Chemistry and Hematology family.

Hospitals file this code under descriptions such as HC Protein C Activity.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Blood test for protein C activity (CPT 85303) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-85303-blood-test-for-protein-c-activity