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Procedure price report · Laboratory - Chemistry and Hematology

Enzyme activity test using radioactive method

CPT 82658the billing code this page is about

Measures the activity of one specific enzyme in blood cells, cultured cells, or tissue using a radioactive substrate; billed once per specimen tested.

Hospitals typically charge $183 cash for this outpatient procedure — the median across 494 hospitals that filed a usable cash price; the average of the middle 60% is $182. Most fall between $58 and $377 (20th–80th percentile).

Hospitals
494
States
41
Filings dated
Dec 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 494 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$44$68$183$308$616

The most expensive tenth of hospitals charges at least 14× what the cheapest tenth charges ($44 vs $616).

How the prices are spread

$31 – $44: 20 hospitals$31$44 – $62: 67 hospitals$62 – $88: 51 hospitals$62$88 – $126: 46 hospitals$126 – $179: 31 hospitals$126$179 – $254: 89 hospitals$254 – $361: 66 hospitals$254$361 – $513: 32 hospitals$513 – $729: 33 hospitals$513$729 – $1,037: 17 hospitals$729median $183price bands are equal on a log scale
Hospitals per price band (452 of 494 — the bands cover the 5th to 95th percentile)
FromToHospitals
$31$4420
$44$6267
$62$8851
$88$12646
$126$17931
$179$25489
$254$36166
$361$51332
$513$72933
$729$1,03717

By state

The median cash price in each state, against the national median of $183.

Alaska: no hospital in the corpus filed a usable priceAKMaine: no hospital in the corpus filed a usable priceMEVermont: 1 hospital filed a usable price — fewer than 10, so no figureVTNew Hampshire: 1 hospital filed a usable price — fewer than 10, so no figureNHWashington: median $68 across 13 hospitalsWA$68Idaho: no hospital in the corpus filed a usable priceIDMontana: no hospital in the corpus filed a usable priceMTNorth Dakota: 4 hospitals filed a usable price — fewer than 10, so no figureNDMinnesota: median $250 across 10 hospitalsMN$250Illinois: median $48 across 26 hospitalsIL$48Wisconsin: 4 hospitals filed a usable price — fewer than 10, so no figureWIMichigan: median $226 across 14 hospitalsMI$226New York: median $59 across 29 hospitalsNY$59Massachusetts: 3 hospitals filed a usable price — fewer than 10, so no figureMAOregon: 4 hospitals filed a usable price — fewer than 10, so no figureORNevada: 1 hospital filed a usable price — fewer than 10, so no figureNVWyoming: 1 hospital filed a usable price — fewer than 10, so no figureWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $89 across 14 hospitalsIA$89Indiana: median $85 across 18 hospitalsIN$85Ohio: median $373 across 62 hospitalsOH$373Pennsylvania: median $44 across 26 hospitalsPA$44New Jersey: median $48 across 33 hospitalsNJ$48Connecticut: 4 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 1 hospital filed a usable price — fewer than 10, so no figureRICalifornia: median $183 across 46 hospitalsCA$183Utah: 3 hospitals filed a usable price — fewer than 10, so no figureUTColorado: 3 hospitals filed a usable price — fewer than 10, so no figureCONebraska: no hospital in the corpus filed a usable priceNEMissouri: 9 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: median $1,943 across 11 hospitalsKY$1,943West Virginia: no hospital in the corpus filed a usable priceWVVirginia: median $232 across 12 hospitalsVA$232Maryland: 4 hospitals filed a usable price — fewer than 10, so no figureMDDelaware: no hospital in the corpus filed a usable priceDEArizona: 4 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: 1 hospital filed a usable price — fewer than 10, so no figureNMKansas: 5 hospitals filed a usable price — fewer than 10, so no figureKSArkansas: 3 hospitals filed a usable price — fewer than 10, so no figureARTennessee: 8 hospitals filed a usable price — fewer than 10, so no figureTNNorth Carolina: no hospital in the corpus filed a usable priceNCSouth Carolina: 3 hospitals filed a usable price — fewer than 10, so no figureSCOklahoma: median $78 across 16 hospitalsOK$78Louisiana: 6 hospitals filed a usable price — fewer than 10, so no figureLAMississippi: 6 hospitals filed a usable price — fewer than 10, so no figureMSAlabama: 1 hospital filed a usable price — fewer than 10, so no figureALGeorgia: 9 hospitals filed a usable price — fewer than 10, so no figureGAHawaii: 7 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $255 across 57 hospitalsTX$255Florida: median $117 across 11 hospitalsFL$117
Cash price by state, most expensive first. National median $183. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Kentucky KY11$1,943+961%$616 – $1,943
Ohio OH62$373+104%$198 – $799
Texas TX57$255+39%$127 – $284
Minnesota MN10$250+37%$250 – $265
Virginia VA12$232+26%$232 – $360
Michigan MI14$226+23%$61 – $454
California CA46$1830%$183 – $249
Florida FL11$117−36%$117 – $122
Iowa IA14$89−52%$89 – $132
Indiana IN18$85−54%$64 – $147
Oklahoma OK16$78−58%$78 – $128
Washington WA13$68−63%$68 – $289
New York NY29$59−68%$44 – $162
New Jersey NJ33$48−74%$44 – $205
Illinois IL26$48−74%$31 – $649
Pennsylvania PA26$44−76%$30 – $208
Georgia GA9not enough hospitals filed a usable price
Missouri MO9not enough hospitals filed a usable price
Tennessee TN8not enough hospitals filed a usable price
Hawaii HI7not enough hospitals filed a usable price
Louisiana LA6not enough hospitals filed a usable price
Mississippi MS6not enough hospitals filed a usable price
Kansas KS5not enough hospitals filed a usable price
Arizona AZ4not enough hospitals filed a usable price
Connecticut CT4not enough hospitals filed a usable price
Maryland MD4not enough hospitals filed a usable price
North Dakota ND4not enough hospitals filed a usable price
Oregon OR4not enough hospitals filed a usable price
Wisconsin WI4not enough hospitals filed a usable price
Arkansas AR3not enough hospitals filed a usable price
Colorado CO3not enough hospitals filed a usable price
Massachusetts MA3not enough hospitals filed a usable price
South Carolina SC3not enough hospitals filed a usable price
Utah UT3not enough hospitals filed a usable price
Alabama AL1not enough hospitals filed a usable price
New Hampshire NH1not enough hospitals filed a usable price
New Mexico NM1not enough hospitals filed a usable price
Nevada NV1not enough hospitals filed a usable price
Rhode Island RI1not enough hospitals filed a usable price
Vermont VT1not enough hospitals filed a usable price
Wyoming WY1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $183.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care412$183$51 – $312
Children’s32$405$142 – $655
Critical access48$185$75 – $616
Ownership
For-profit53$255$64 – $454
Government44$117$44 – $409
Non-profit395$183$61 – $360
System affiliation
Part of a system446$183$61 – $373
Independent48$142$51 – $521

Cash price vs list price

Median list price (chargemaster)$368
Median cash price$183
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

330 hospitals filed a usable inpatient cash price for this code. The median is $249 and the average of the middle 60% is $237; most fall between $89 and $468.

Cash price percentiles, inpatient, across 330 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$68$122$249$373$655

The most expensive tenth of hospitals charges at least 9.7× what the cheapest tenth charges ($68 vs $655).

Of the 374 hospitals that filed this code inpatient, 330 gave a usable cash price; 21 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 23 a list price only.

How complete is this

494 of the 3,956 hospitals with a price file in our corpus (12%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 542 hospitals that filed this code at all gave us
Usable cash price — counted494
Cash price carrying a plausibility flag — shown on the compare tool, excluded here25
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded22
Hospitals that filed this code542

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 5, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Laboratory - Chemistry and Hematology family.

Hospitals file this code under descriptions such as ENZYME CELL ACTIVITY RA.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Enzyme activity test using radioactive method (CPT 82658) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-82658-enzyme-activity-test-using-radioactive-method