HRHospitalRates.comCompare prices

Procedure price report · Laboratory - Chemistry and Hematology

Enzyme activity test on blood or tissue cells

CPT 82657the billing code this page is about

Measures how well one specific enzyme works in blood cells, cultured cells, or tissue using a non-radioactive method; billed once per specimen tested.

Hospitals typically charge $111 cash for this outpatient procedure — the median across 2,463 hospitals that filed a usable cash price; the average of the middle 60% is $123. Most fall between $42 and $262 (20th–80th percentile).

Hospitals
2,463
States
50
Filings dated
Dec 2023 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 2,463 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$26$52$111$223$395

The most expensive tenth of hospitals charges at least 15× what the cheapest tenth charges ($26 vs $395).

How the prices are spread

$21 – $29: 174 hospitals$21$29 – $40: 190 hospitals$40 – $56: 170 hospitals$40$56 – $77: 264 hospitals$77 – $107: 279 hospitals$77$107 – $149: 329 hospitals$149 – $206: 258 hospitals$149$206 – $286: 226 hospitals$286 – $396: 205 hospitals$286$396 – $549: 123 hospitals$396median $111price bands are equal on a log scale
Hospitals per price band (2,218 of 2,463 — the bands cover the 5th to 95th percentile)
FromToHospitals
$21$29174
$29$40190
$40$56170
$56$77264
$77$107279
$107$149329
$149$206258
$206$286226
$286$396205
$396$549123

By state

The median cash price in each state, against the national median of $111.

Alaska: median $121 across 10 hospitalsAK$121Maine: median $127 across 24 hospitalsME$127Vermont: median $218 across 11 hospitalsVT$218New Hampshire: median $153 across 15 hospitalsNH$153Washington: median $82 across 54 hospitalsWA$82Idaho: median $174 across 17 hospitalsID$174Montana: median $162 across 17 hospitalsMT$162North Dakota: median $111 across 15 hospitalsND$111Minnesota: median $123 across 61 hospitalsMN$123Illinois: median $191 across 111 hospitalsIL$191Wisconsin: median $175 across 93 hospitalsWI$175Michigan: median $125 across 70 hospitalsMI$125New York: median $54 across 99 hospitalsNY$54Massachusetts: median $141 across 43 hospitalsMA$141Oregon: median $133 across 27 hospitalsOR$133Nevada: median $80 across 14 hospitalsNV$80Wyoming: median $176 across 13 hospitalsWY$176South Dakota: median $141 across 13 hospitalsSD$141Iowa: median $110 across 54 hospitalsIA$110Indiana: median $128 across 79 hospitalsIN$128Ohio: median $133 across 118 hospitalsOH$133Pennsylvania: median $103 across 102 hospitalsPA$103New Jersey: median $26 across 51 hospitalsNJ$26Connecticut: median $104 across 15 hospitalsCT$104Rhode Island: 7 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $94 across 99 hospitalsCA$94Utah: median $45 across 38 hospitalsUT$45Colorado: median $135 across 56 hospitalsCO$135Nebraska: median $66 across 53 hospitalsNE$66Missouri: median $50 across 66 hospitalsMO$50Kentucky: median $144 across 50 hospitalsKY$144West Virginia: median $129 across 33 hospitalsWV$129Virginia: median $115 across 61 hospitalsVA$115Maryland: median $109 across 38 hospitalsMD$109Delaware: 5 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $131 across 33 hospitalsAZ$131New Mexico: median $122 across 17 hospitalsNM$122Kansas: median $151 across 42 hospitalsKS$151Arkansas: median $56 across 17 hospitalsAR$56Tennessee: median $58 across 54 hospitalsTN$58North Carolina: median $138 across 74 hospitalsNC$138South Carolina: median $248 across 50 hospitalsSC$248Oklahoma: median $63 across 57 hospitalsOK$63Louisiana: median $53 across 42 hospitalsLA$53Mississippi: median $53 across 43 hospitalsMS$53Alabama: median $133 across 28 hospitalsAL$133Georgia: median $110 across 85 hospitalsGA$110Hawaii: median $96 across 12 hospitalsHI$96Texas: median $143 across 174 hospitalsTX$143Florida: median $78 across 103 hospitalsFL$78
Cash price by state, most expensive first. National median $111. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
South Carolina SC50$248+123%$83 – $352
Vermont VT11$218+96%$116 – $410
Illinois IL111$191+72%$59 – $467
Wyoming WY13$176+58%$60 – $377
Wisconsin WI93$175+57%$82 – $299
Idaho ID17$174+57%$78 – $199
Montana MT17$162+46%$139 – $298
New Hampshire NH15$153+38%$36 – $408
Kansas KS42$151+36%$61 – $361
Kentucky KY50$144+29%$29 – $282
Texas TX174$143+29%$65 – $360
Massachusetts MA43$141+27%$45 – $247
South Dakota SD13$141+26%$141 – $334
North Carolina NC74$138+24%$99 – $425
Colorado CO56$135+21%$76 – $295
Oregon OR27$133+20%$74 – $225
Alabama AL28$133+20%$28 – $501
Ohio OH118$133+19%$74 – $250
Arizona AZ33$131+18%$34 – $344
West Virginia WV33$129+16%$14 – $315
Indiana IN79$128+15%$36 – $209
Maine ME24$127+14%$75 – $457
Michigan MI70$125+12%$24 – $274
Minnesota MN61$123+11%$36 – $176
New Mexico NM17$122+9%$88 – $317
Alaska AK10$121+9%$101 – $302
Virginia VA61$115+3%$56 – $213
North Dakota ND15$1110%$77 – $200
Iowa IA54$110−1%$64 – $272
Georgia GA85$110−2%$63 – $236
Maryland MD38$109−2%$86 – $130
Connecticut CT15$104−6%$67 – $197
Pennsylvania PA102$103−7%$26 – $260
Hawaii HI12$96−13%$44 – $144
California CA99$94−16%$38 – $133
Washington WA54$82−26%$50 – $121
Nevada NV14$80−28%$43 – $114
Florida FL103$78−30%$39 – $200
Nebraska NE53$66−40%$22 – $315
Oklahoma OK57$63−44%$23 – $195
Tennessee TN54$58−48%$32 – $234
Arkansas AR17$56−50%$15 – $135
New York NY99$54−51%$30 – $189
Louisiana LA42$53−52%$29 – $166
Mississippi MS43$53−53%$13 – $158
Missouri MO66$50−55%$19 – $183
Utah UT38$45−60%$38 – $329
New Jersey NJ51$26−77%$24 – $107
Rhode Island RI7not enough hospitals filed a usable price
Delaware DE5not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $111.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care1,858$102$39 – $248
Children’s51$117$38 – $204
Critical access545$139$53 – $315
Ownership
For-profit319$125$48 – $360
Government380$125$52 – $302
Non-profit1,755$106$38 – $247
System affiliation
Part of a system2,086$105$39 – $259
Independent377$135$56 – $285

Cash price vs list price

Median list price (chargemaster)$188
Median cash price$111
Cash as a share of list, median hospital60%

At the typical hospital, asking for the cash price cuts the list price by about 40%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

1,748 hospitals filed a usable inpatient cash price for this code. The median is $111 and the average of the middle 60% is $122; most fall between $45 and $248.

Cash price percentiles, inpatient, across 1,748 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$32$58$111$209$352

The most expensive tenth of hospitals charges at least 11× what the cheapest tenth charges ($32 vs $352).

Of the 1,942 hospitals that filed this code inpatient, 1,748 gave a usable cash price; 106 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 88 a list price only.

How complete is this

2,463 of the 3,956 hospitals with a price file in our corpus (62%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 2,701 hospitals that filed this code at all gave us
Usable cash price — counted2,463
Cash price carrying a plausibility flag — shown on the compare tool, excluded here138
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded2
An estimate rather than a filed cash price — excluded1
A list price only, no cash figure — excluded97
Hospitals that filed this code2,701

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Laboratory - Chemistry and Hematology family.

Hospitals file this code under descriptions such as HC Thiopurine Methyltransferase, RBC.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Enzyme activity test on blood or tissue cells (CPT 82657) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-82657-enzyme-activity-test-on-blood-or-tissue-cells