Procedure price report · Laboratory - Chemistry and Hematology

Alpha-fetoprotein blood test

CPT code CPT 82105the billing code this page is about

Blood test that measures the level of alpha-fetoprotein, a protein used in pregnancy screening and in monitoring certain tumors.

Hospitals typically charge $75 cash for this outpatient procedure — the median across 3,328 hospitals that filed a usable cash price; the average of the middle 60% is $79. Most fall between $33 and $143 (20th–80th percentile).

Hospitals
3,328
States
50
Filings dated
Aug 2022 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 3,328 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$19$39$75$127$207

The most expensive tenth of hospitals charges at least 11× what the cheapest tenth charges ($19 vs $207).

How the prices are spread

$12 – $16: 83 hospitals$12$16 – $22: 184 hospitals$22 – $30: 187 hospitals$22$30 – $42: 327 hospitals$42 – $58: 355 hospitals$42$58 – $80: 452 hospitals$80 – $111: 493 hospitals$80$111 – $153: 495 hospitals$153 – $212: 272 hospitals$153$212 – $293: 162 hospitals$212median $75price bands are equal on a log scale
Hospitals per price band (3,010 of 3,328 — the bands cover the 5th to 95th percentile)
FromToHospitals
$12$1683
$16$22184
$22$30187
$30$42327
$42$58355
$58$80452
$80$111493
$111$153495
$153$212272
$212$293162

By state

The median cash price in each state, against the national median of $75.

Alaska: median $73 across 19 hospitalsAK$73Maine: median $67 across 28 hospitalsME$67Vermont: median $94 across 14 hospitalsVT$94New Hampshire: median $94 across 25 hospitalsNH$94Washington: median $78 across 77 hospitalsWA$78Idaho: median $74 across 23 hospitalsID$74Montana: median $86 across 30 hospitalsMT$86North Dakota: median $104 across 35 hospitalsND$104Minnesota: median $48 across 105 hospitalsMN$48Illinois: median $116 across 140 hospitalsIL$116Wisconsin: median $83 across 103 hospitalsWI$83Michigan: median $48 across 98 hospitalsMI$48New York: median $50 across 119 hospitalsNY$50Massachusetts: median $102 across 52 hospitalsMA$102Oregon: median $70 across 50 hospitalsOR$70Nevada: median $82 across 20 hospitalsNV$82Wyoming: median $79 across 16 hospitalsWY$79South Dakota: median $144 across 39 hospitalsSD$144Iowa: median $90 across 89 hospitalsIA$90Indiana: median $86 across 94 hospitalsIN$86Ohio: median $60 across 140 hospitalsOH$60Pennsylvania: median $85 across 121 hospitalsPA$85New Jersey: median $19 across 57 hospitalsNJ$19Connecticut: median $80 across 23 hospitalsCT$80Rhode Island: median $80 across 10 hospitalsRI$80California: median $65 across 144 hospitalsCA$65Utah: median $77 across 41 hospitalsUT$77Colorado: median $97 across 70 hospitalsCO$97Nebraska: median $103 across 78 hospitalsNE$103Missouri: median $77 across 76 hospitalsMO$77Kentucky: median $92 across 67 hospitalsKY$92West Virginia: median $60 across 43 hospitalsWV$60Virginia: median $103 across 73 hospitalsVA$103Maryland: median $41 across 41 hospitalsMD$41Delaware: 7 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $63 across 39 hospitalsAZ$63New Mexico: median $111 across 29 hospitalsNM$111Kansas: median $89 across 89 hospitalsKS$89Arkansas: median $83 across 38 hospitalsAR$83Tennessee: median $46 across 80 hospitalsTN$46North Carolina: median $50 across 89 hospitalsNC$50South Carolina: median $114 across 53 hospitalsSC$114Oklahoma: median $58 across 72 hospitalsOK$58Louisiana: median $57 across 51 hospitalsLA$57Mississippi: median $39 across 55 hospitalsMS$39Alabama: median $73 across 44 hospitalsAL$73Georgia: median $80 across 108 hospitalsGA$80Hawaii: median $85 across 20 hospitalsHI$85Texas: median $99 across 246 hospitalsTX$99Florida: median $30 across 148 hospitalsFL$30
Cash price by state, most expensive first. National median $75. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
South Dakota SD39$144+90%$93 – $242
Illinois IL140$116+54%$64 – $223
South Carolina SC53$114+51%$51 – $117
New Mexico NM29$111+47%$54 – $219
North Dakota ND35$104+39%$29 – $130
Nebraska NE78$103+36%$50 – $147
Virginia VA73$103+36%$29 – $187
Massachusetts MA52$102+35%$51 – $163
Texas TX246$99+32%$31 – $253
Colorado CO70$97+28%$45 – $162
Vermont VT14$94+25%$41 – $138
New Hampshire NH25$94+24%$18 – $195
Kentucky KY67$92+21%$40 – $212
Iowa IA89$90+20%$57 – $142
Kansas KS89$89+18%$62 – $126
Indiana IN94$86+15%$42 – $130
Montana MT30$86+14%$78 – $116
Pennsylvania PA121$85+13%$26 – $197
Hawaii HI20$85+12%$45 – $132
Arkansas AR38$83+10%$35 – $97
Wisconsin WI103$83+10%$53 – $127
Nevada NV20$82+9%$10 – $119
Georgia GA108$80+6%$39 – $184
Rhode Island RI10$80+6%$39 – $134
Connecticut CT23$80+6%$61 – $140
Wyoming WY16$79+5%$34 – $115
Washington WA77$78+4%$43 – $116
Utah UT41$77+2%$65 – $114
Missouri MO76$77+1%$51 – $140
Idaho ID23$74−1%$14 – $120
Alabama AL44$73−3%$26 – $152
Alaska AK19$73−3%$31 – $185
Oregon OR50$70−7%$45 – $93
Maine ME28$67−11%$29 – $115
California CA144$65−14%$9 – $157
Arizona AZ39$63−16%$24 – $178
West Virginia WV43$60−21%$6 – $132
Ohio OH140$60−21%$40 – $103
Oklahoma OK72$58−24%$36 – $116
Louisiana LA51$57−24%$30 – $94
New York NY119$50−34%$20 – $192
North Carolina NC89$50−34%$32 – $133
Minnesota MN105$48−36%$22 – $125
Michigan MI98$48−36%$18 – $74
Tennessee TN80$46−39%$29 – $136
Maryland MD41$41−46%$32 – $49
Mississippi MS55$39−48%$20 – $63
Florida FL148$30−60%$11 – $146
New Jersey NJ57$19−74%$18 – $57
Delaware DE7not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $75.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care2,283$71$28 – $144
Children’s63$128$45 – $215
Critical access972$86$43 – $138
Ownership
For-profit461$101$32 – $281
Government635$77$37 – $132
Non-profit2,222$73$31 – $134
System affiliation
Part of a system2,693$76$32 – $145
Independent635$74$36 – $127

Cash price vs list price

Median list price (chargemaster)$126
Median cash price$75
Cash as a share of list, median hospital65%

At the typical hospital, asking for the cash price cuts the list price by about 35%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

2,238 hospitals filed a usable inpatient cash price for this code. The median is $77 and the average of the middle 60% is $80; most fall between $34 and $138.

Cash price percentiles, inpatient, across 2,238 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$20$41$77$125$187

The most expensive tenth of hospitals charges at least 9.5× what the cheapest tenth charges ($20 vs $187).

Of the 2,478 hospitals that filed this code inpatient, 2,238 gave a usable cash price; 128 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 112 a list price only.

How complete is this

3,328 of the 3,956 hospitals with a price file in our corpus (84%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 3,627 hospitals that filed this code at all gave us
Usable cash price — counted3,328
Cash price carrying a plausibility flag — shown on the compare tool, excluded here166
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded0
An estimate rather than a filed cash price — excluded1
A list price only, no cash figure — excluded132
Hospitals that filed this code3,627

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between July 20, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Hospitals file this code under descriptions such as HC Alpha Feto Protein, Serum, Non Pregnant.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Alpha-fetoprotein blood test (CPT 82105) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-82105-alpha-fetoprotein-blood-test