Procedure price report · Other Laboratory

Drug test measuring 1 to 3 unlisted substances

CPT code CPT 80375the billing code this page is about

Laboratory testing that specifically identifies and, if done, measures the amount of one to three drugs or substances that have no code of their own.

Hospitals typically charge $112 cash for this outpatient procedure — the median across 1,562 hospitals that filed a usable cash price; the average of the middle 60% is $120. Most fall between $52 and $224 (20th–80th percentile).

Hospitals
1,562
States
50
Filings dated
Nov 2023 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 25, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 1,562 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$32$61$112$195$351

The most expensive tenth of hospitals charges at least 11× what the cheapest tenth charges ($32 vs $351).

How the prices are spread

$18 – $25: 50 hospitals$18$25 – $36: 52 hospitals$36 – $51: 126 hospitals$36$51 – $73: 179 hospitals$73 – $103: 239 hospitals$73$103 – $146: 238 hospitals$146 – $208: 253 hospitals$146$208 – $295: 131 hospitals$295 – $420: 99 hospitals$295$420 – $596: 42 hospitals$420median $112price bands are equal on a log scale
Hospitals per price band (1,409 of 1,562 — the bands cover the 5th to 95th percentile)
FromToHospitals
$18$2550
$25$3652
$36$51126
$51$73179
$73$103239
$103$146238
$146$208253
$208$295131
$295$42099
$420$59642

By state

The median cash price in each state, against the national median of $112.

Alaska: median $115 across 12 hospitalsAK$115Maine: median $117 across 12 hospitalsME$117Vermont: median $162 across 11 hospitalsVT$162New Hampshire: 5 hospitals filed a usable price — fewer than 10, so no figureNHWashington: median $108 across 35 hospitalsWA$108Idaho: 6 hospitals filed a usable price — fewer than 10, so no figureIDMontana: 8 hospitals filed a usable price — fewer than 10, so no figureMTNorth Dakota: median $84 across 14 hospitalsND$84Minnesota: median $67 across 35 hospitalsMN$67Illinois: median $104 across 74 hospitalsIL$104Wisconsin: median $85 across 56 hospitalsWI$85Michigan: median $93 across 58 hospitalsMI$93New York: median $99 across 57 hospitalsNY$99Massachusetts: median $120 across 34 hospitalsMA$120Oregon: median $96 across 21 hospitalsOR$96Nevada: 7 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 8 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: 5 hospitals filed a usable price — fewer than 10, so no figureSDIowa: median $126 across 31 hospitalsIA$126Indiana: median $90 across 35 hospitalsIN$90Ohio: median $90 across 59 hospitalsOH$90Pennsylvania: median $225 across 40 hospitalsPA$225New Jersey: median $40 across 28 hospitalsNJ$40Connecticut: 9 hospitals filed a usable price — fewer than 10, so no figureCTRhode Island: 3 hospitals filed a usable price — fewer than 10, so no figureRICalifornia: median $80 across 68 hospitalsCA$80Utah: median $1,400 across 29 hospitalsUT$1,400Colorado: median $123 across 36 hospitalsCO$123Nebraska: median $200 across 29 hospitalsNE$200Missouri: median $142 across 36 hospitalsMO$142Kentucky: median $135 across 38 hospitalsKY$135West Virginia: median $130 across 29 hospitalsWV$130Virginia: median $106 across 21 hospitalsVA$106Maryland: median $63 across 28 hospitalsMD$63Delaware: 4 hospitals filed a usable price — fewer than 10, so no figureDEArizona: median $74 across 13 hospitalsAZ$74New Mexico: 7 hospitals filed a usable price — fewer than 10, so no figureNMKansas: median $143 across 32 hospitalsKS$143Arkansas: median $166 across 19 hospitalsAR$166Tennessee: median $74 across 46 hospitalsTN$74North Carolina: median $93 across 53 hospitalsNC$93South Carolina: median $164 across 31 hospitalsSC$164Oklahoma: median $134 across 31 hospitalsOK$134Louisiana: median $34 across 30 hospitalsLA$34Mississippi: median $68 across 32 hospitalsMS$68Alabama: median $61 across 16 hospitalsAL$61Georgia: median $95 across 56 hospitalsGA$95Hawaii: median $338 across 10 hospitalsHI$338Texas: median $172 across 132 hospitalsTX$172Florida: median $106 across 73 hospitalsFL$106
Cash price by state, most expensive first. National median $112. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
Utah UT29$1,400+1154%$750 – $1,647
Hawaii HI10$338+203%$94 – $369
Pennsylvania PA40$225+102%$80 – $865
Nebraska NE29$200+79%$107 – $363
Texas TX132$172+54%$104 – $289
Arkansas AR19$166+49%$56 – $171
South Carolina SC31$164+47%$91 – $227
Vermont VT11$162+45%$93 – $183
Kansas KS32$143+28%$83 – $313
Missouri MO36$142+27%$45 – $228
Kentucky KY38$135+21%$112 – $263
Oklahoma OK31$134+20%$49 – $204
West Virginia WV29$130+16%$39 – $155
Iowa IA31$126+13%$93 – $200
Colorado CO36$123+10%$91 – $209
Massachusetts MA34$120+8%$48 – $311
Maine ME12$117+5%$89 – $184
Alaska AK12$115+3%$79 – $385
Washington WA35$108−3%$74 – $168
Florida FL73$106−5%$44 – $237
Virginia VA21$106−5%$7 – $243
Illinois IL74$104−6%$56 – $234
New York NY57$99−11%$35 – $401
Oregon OR21$96−14%$59 – $141
Georgia GA56$95−15%$61 – $215
North Carolina NC53$93−17%$65 – $170
Michigan MI58$93−17%$46 – $134
Ohio OH59$90−19%$18 – $229
Indiana IN35$90−20%$51 – $255
Wisconsin WI56$85−24%$63 – $177
North Dakota ND14$84−24%$81 – $268
California CA68$80−28%$49 – $89
Tennessee TN46$74−34%$7 – $147
Arizona AZ13$74−34%$39 – $284
Mississippi MS32$68−39%$24 – $161
Minnesota MN35$67−40%$12 – $127
Maryland MD28$63−44%$23 – $143
Alabama AL16$61−46%$51 – $102
New Jersey NJ28$40−65%$31 – $279
Louisiana LA30$34−70%$15 – $106
Connecticut CT9not enough hospitals filed a usable price
Montana MT8not enough hospitals filed a usable price
Wyoming WY8not enough hospitals filed a usable price
New Mexico NM7not enough hospitals filed a usable price
Nevada NV7not enough hospitals filed a usable price
Idaho ID6not enough hospitals filed a usable price
New Hampshire NH5not enough hospitals filed a usable price
South Dakota SD5not enough hospitals filed a usable price
Delaware DE4not enough hospitals filed a usable price
Rhode Island RI3not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $112.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care1,178$110$49 – $227
Children’s30$110$53 – $201
Critical access350$118$56 – $212
Ownership
For-profit202$155$61 – $341
Government256$104$60 – $202
Non-profit1,100$110$48 – $211
System affiliation
Part of a system1,308$111$49 – $227
Independent254$112$59 – $218

Cash price vs list price

Median list price (chargemaster)$183
Median cash price$112
Cash as a share of list, median hospital65%

At the typical hospital, asking for the cash price cuts the list price by about 35%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

1,085 hospitals filed a usable inpatient cash price for this code. The median is $113 and the average of the middle 60% is $120; most fall between $55 and $218.

Cash price percentiles, inpatient, across 1,085 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$35$62$113$189$338

The most expensive tenth of hospitals charges at least 9.6× what the cheapest tenth charges ($35 vs $338).

Of the 1,207 hospitals that filed this code inpatient, 1,085 gave a usable cash price; 63 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 59 a list price only.

How complete is this

1,562 of the 3,956 hospitals with a price file in our corpus (39%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 1,742 hospitals that filed this code at all gave us
Usable cash price — counted1,562
Cash price carrying a plausibility flag — shown on the compare tool, excluded here77
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded102
Hospitals that filed this code1,742

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 25, 2026; the figures were computed September 25, 2026 from filings loaded through September 25, 2026. The percentiles and averages use only the “counted” row.

Hospitals file this code under descriptions such as HC Clonidine (Catapres).

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Drug test measuring 1 to 3 unlisted substances (CPT 80375) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-80375-drug-test-measuring-1-to-3-unlisted-substances