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Procedure price report · Other Laboratory

Confirmatory test for 3 to 5 serotonin antidepressants

CPT 80333the billing code this page is about

A definitive laboratory test measuring three to five antidepressant drugs of the serotonin-acting type in one sample; billed once for the group.

Hospitals typically charge $54 cash for this outpatient procedure — the median across 412 hospitals that filed a usable cash price; the average of the middle 60% is $58. Most fall between $14 and $127 (20th–80th percentile).

Hospitals
412
States
46
Filings dated
Jan 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 412 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$6$16$54$105$200

The most expensive tenth of hospitals charges at least 31× what the cheapest tenth charges ($6 vs $200).

How the prices are spread

$5 – $8: 41 hospitals$5$8 – $11: 7 hospitals$11 – $17: 52 hospitals$11$17 – $26: 18 hospitals$26 – $39: 31 hospitals$26$39 – $59: 56 hospitals$59 – $88: 67 hospitals$59$88 – $133: 50 hospitals$133 – $200: 38 hospitals$133$200 – $301: 21 hospitals$200median $54price bands are equal on a log scale
Hospitals per price band (381 of 412 — the bands cover the 5th to 95th percentile)
FromToHospitals
$5$841
$8$117
$11$1752
$17$2618
$26$3931
$39$5956
$59$8867
$88$13350
$133$20038
$200$30121

By state

The median cash price in each state, against the national median of $54.

Alaska: 2 hospitals filed a usable price — fewer than 10, so no figureAKMaine: 2 hospitals filed a usable price — fewer than 10, so no figureMEVermont: 4 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: 1 hospital filed a usable price — fewer than 10, so no figureNHWashington: median $98 across 19 hospitalsWA$98Idaho: 2 hospitals filed a usable price — fewer than 10, so no figureIDMontana: 1 hospital filed a usable price — fewer than 10, so no figureMTNorth Dakota: 2 hospitals filed a usable price — fewer than 10, so no figureNDMinnesota: median $49 across 22 hospitalsMN$49Illinois: 9 hospitals filed a usable price — fewer than 10, so no figureILWisconsin: 5 hospitals filed a usable price — fewer than 10, so no figureWIMichigan: 4 hospitals filed a usable price — fewer than 10, so no figureMINew York: median $34 across 22 hospitalsNY$34Massachusetts: median $49 across 15 hospitalsMA$49Oregon: 3 hospitals filed a usable price — fewer than 10, so no figureORNevada: 2 hospitals filed a usable price — fewer than 10, so no figureNVWyoming: 4 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: 5 hospitals filed a usable price — fewer than 10, so no figureSDIowa: median $72 across 14 hospitalsIA$72Indiana: 6 hospitals filed a usable price — fewer than 10, so no figureINOhio: median $17 across 28 hospitalsOH$17Pennsylvania: 7 hospitals filed a usable price — fewer than 10, so no figurePANew Jersey: median $289 across 10 hospitalsNJ$289Connecticut: 1 hospital filed a usable price — fewer than 10, so no figureCTRhode Island: no hospital in the corpus filed a usable priceRICalifornia: median $16 across 39 hospitalsCA$16Utah: no hospital in the corpus filed a usable priceUTColorado: 6 hospitals filed a usable price — fewer than 10, so no figureCONebraska: 5 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: median $105 across 16 hospitalsMO$105Kentucky: 7 hospitals filed a usable price — fewer than 10, so no figureKYWest Virginia: median $5 across 13 hospitalsWV$5Virginia: 5 hospitals filed a usable price — fewer than 10, so no figureVAMaryland: median $161 across 11 hospitalsMD$161Delaware: 2 hospitals filed a usable price — fewer than 10, so no figureDEArizona: no hospital in the corpus filed a usable priceAZNew Mexico: no hospital in the corpus filed a usable priceNMKansas: 7 hospitals filed a usable price — fewer than 10, so no figureKSArkansas: 9 hospitals filed a usable price — fewer than 10, so no figureARTennessee: median $35 across 12 hospitalsTN$35North Carolina: median $3 across 11 hospitalsNC$3South Carolina: 4 hospitals filed a usable price — fewer than 10, so no figureSCOklahoma: 6 hospitals filed a usable price — fewer than 10, so no figureOKLouisiana: 7 hospitals filed a usable price — fewer than 10, so no figureLAMississippi: 2 hospitals filed a usable price — fewer than 10, so no figureMSAlabama: 6 hospitals filed a usable price — fewer than 10, so no figureALGeorgia: 4 hospitals filed a usable price — fewer than 10, so no figureGAHawaii: 5 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $83 across 17 hospitalsTX$83Florida: median $24 across 28 hospitalsFL$24
Cash price by state, most expensive first. National median $54. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
New Jersey NJ10$289+435%$49 – $304
Maryland MD11$161+197%$17 – $219
Missouri MO16$105+94%$98 – $123
Washington WA19$98+81%$58 – $202
Texas TX17$83+53%$83 – $83
Iowa IA14$72+34%$68 – $72
Massachusetts MA15$49−9%$40 – $109
Minnesota MN22$49−10%$44 – $75
Tennessee TN12$35−35%$13 – $136
New York NY22$34−37%$23 – $114
Florida FL28$24−56%$7 – $31
Ohio OH28$17−69%$14 – $207
California CA39$16−70%$6 – $17
West Virginia WV13$5−91%$5 – $68
North Carolina NC11$3−94%$3 – $32
Arkansas AR9not enough hospitals filed a usable price
Illinois IL9not enough hospitals filed a usable price
Kansas KS7not enough hospitals filed a usable price
Kentucky KY7not enough hospitals filed a usable price
Louisiana LA7not enough hospitals filed a usable price
Pennsylvania PA7not enough hospitals filed a usable price
Alabama AL6not enough hospitals filed a usable price
Colorado CO6not enough hospitals filed a usable price
Indiana IN6not enough hospitals filed a usable price
Oklahoma OK6not enough hospitals filed a usable price
Hawaii HI5not enough hospitals filed a usable price
Nebraska NE5not enough hospitals filed a usable price
South Dakota SD5not enough hospitals filed a usable price
Virginia VA5not enough hospitals filed a usable price
Wisconsin WI5not enough hospitals filed a usable price
Georgia GA4not enough hospitals filed a usable price
Michigan MI4not enough hospitals filed a usable price
South Carolina SC4not enough hospitals filed a usable price
Vermont VT4not enough hospitals filed a usable price
Wyoming WY4not enough hospitals filed a usable price
Oregon OR3not enough hospitals filed a usable price
Alaska AK2not enough hospitals filed a usable price
Delaware DE2not enough hospitals filed a usable price
Idaho ID2not enough hospitals filed a usable price
Maine ME2not enough hospitals filed a usable price
Mississippi MS2not enough hospitals filed a usable price
North Dakota ND2not enough hospitals filed a usable price
Nevada NV2not enough hospitals filed a usable price
Connecticut CT1not enough hospitals filed a usable price
Montana MT1not enough hospitals filed a usable price
New Hampshire NH1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $54.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care305$53$14 – $136
Children’s9fewer than 20 hospitals
Critical access96$59$33 – $110
Ownership
For-profit31$83$33 – $139
Government61$40$6 – $71
Non-profit318$57$14 – $136
System affiliation
Part of a system357$50$14 – $114
Independent55$75$37 – $170

Cash price vs list price

Median list price (chargemaster)$85
Median cash price$54
Cash as a share of list, median hospital65%

At the typical hospital, asking for the cash price cuts the list price by about 35%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

265 hospitals filed a usable inpatient cash price for this code. The median is $49 and the average of the middle 60% is $51; most fall between $13 and $118.

Cash price percentiles, inpatient, across 265 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$6$14$49$90$189

The most expensive tenth of hospitals charges at least 33× what the cheapest tenth charges ($6 vs $189).

Of the 305 hospitals that filed this code inpatient, 265 gave a usable cash price; 30 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 10 a list price only.

How complete is this

412 of the 3,956 hospitals with a price file in our corpus (10%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 459 hospitals that filed this code at all gave us
Usable cash price — counted412
Cash price carrying a plausibility flag — shown on the compare tool, excluded here25
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded5
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded17
Hospitals that filed this code459

Sections not shown for this setting

  • Against Medicare: Medicare has no separately payable national outpatient (OPPS) rate for this code, so there is nothing honest to compare against.
  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 24, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Other Laboratory family.

Hospitals file this code under descriptions such as ANTIDEPRESSANTS LEVELS; 3-5 (SEROTONERGIC CLASS).

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Confirmatory test for 3 to 5 serotonin antidepressants (CPT 80333) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-80333-confirmatory-test-for-3-to-5-serotonin-antidepressants