HRHospitalRates.comCompare prices

Procedure price report · Destruction of lesion of retina and choroid

Light-activated drug therapy for choroid lesion, one eye

CPT 67221the billing code this page is about

Treatment of a lesion under the retina using a light-sensitive drug given by vein and then activated with a laser; this code covers one eye in one session.

Hospitals typically charge $753 cash for this outpatient procedure — the median across 306 hospitals that filed a usable cash price; the average of the middle 60% is $928. Most fall between $427 and $1,844 (20th–80th percentile).

Hospitals
306
States
37
Filings dated
Jun 2024 – Sep 2026
Computed
September 25, 2026
Prices checked
through September 24, 2026

Median: half of hospitals filed less, half more — and it is a price some hospital actually filed. Average of the middle 60%: the mean of the prices between the 20th and 80th percentiles. We never publish the plain average, the lowest or the highest price: the extremes in hospital price files are chargemaster artefacts, not prices anyone pays.

What hospitals charge, from cheapest to most expensive

Cash price percentiles, outpatient, across 306 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$316$507$753$1,535$2,010

The most expensive tenth of hospitals charges at least 6.4× what the cheapest tenth charges ($316 vs $2,010).

How the prices are spread

$208 – $275: 11 hospitals$208$275 – $363: 27 hospitals$363 – $480: 19 hospitals$363$480 – $634: 38 hospitals$634 – $838: 60 hospitals$634$838 – $1,107: 30 hospitals$1,107 – $1,463: 26 hospitals$1,107$1,463 – $1,933: 36 hospitals$1,933 – $2,555: 27 hospitals$1,933$2,555 – $3,376: 3 hospitals$2,555median $753price bands are equal on a log scale
Hospitals per price band (277 of 306 — the bands cover the 5th to 95th percentile)
FromToHospitals
$208$27511
$275$36327
$363$48019
$480$63438
$634$83860
$838$1,10730
$1,107$1,46326
$1,463$1,93336
$1,933$2,55527
$2,555$3,3763

Against Medicare

Medicare pays (OPPS 2026, national rate)$562
Median cash price$753
Cash as a multiple of Medicare1.34×

The Medicare figure is the national unadjusted OPPS rate for this code — what Medicare itself pays a hospital before local wage adjustment. It is a benchmark, not a price anyone is charged.

By state

The median cash price in each state, against the national median of $753.

Alaska: 1 hospital filed a usable price — fewer than 10, so no figureAKMaine: no hospital in the corpus filed a usable priceMEVermont: 2 hospitals filed a usable price — fewer than 10, so no figureVTNew Hampshire: 4 hospitals filed a usable price — fewer than 10, so no figureNHWashington: 4 hospitals filed a usable price — fewer than 10, so no figureWAIdaho: 6 hospitals filed a usable price — fewer than 10, so no figureIDMontana: 1 hospital filed a usable price — fewer than 10, so no figureMTNorth Dakota: no hospital in the corpus filed a usable priceNDMinnesota: 9 hospitals filed a usable price — fewer than 10, so no figureMNIllinois: median $507 across 17 hospitalsIL$507Wisconsin: median $1,844 across 16 hospitalsWI$1,844Michigan: median $756 across 10 hospitalsMI$756New York: median $649 across 23 hospitalsNY$649Massachusetts: 4 hospitals filed a usable price — fewer than 10, so no figureMAOregon: 7 hospitals filed a usable price — fewer than 10, so no figureORNevada: 1 hospital filed a usable price — fewer than 10, so no figureNVWyoming: 2 hospitals filed a usable price — fewer than 10, so no figureWYSouth Dakota: no hospital in the corpus filed a usable priceSDIowa: median $697 across 14 hospitalsIA$697Indiana: no hospital in the corpus filed a usable priceINOhio: 5 hospitals filed a usable price — fewer than 10, so no figureOHPennsylvania: median $597 across 24 hospitalsPA$597New Jersey: median $3,786 across 23 hospitalsNJ$3,786Connecticut: no hospital in the corpus filed a usable priceCTRhode Island: no hospital in the corpus filed a usable priceRICalifornia: median $1,050 across 43 hospitalsCA$1,050Utah: 1 hospital filed a usable price — fewer than 10, so no figureUTColorado: 9 hospitals filed a usable price — fewer than 10, so no figureCONebraska: 3 hospitals filed a usable price — fewer than 10, so no figureNEMissouri: 4 hospitals filed a usable price — fewer than 10, so no figureMOKentucky: 2 hospitals filed a usable price — fewer than 10, so no figureKYWest Virginia: 3 hospitals filed a usable price — fewer than 10, so no figureWVVirginia: no hospital in the corpus filed a usable priceVAMaryland: no hospital in the corpus filed a usable priceMDDelaware: no hospital in the corpus filed a usable priceDEArizona: 2 hospitals filed a usable price — fewer than 10, so no figureAZNew Mexico: no hospital in the corpus filed a usable priceNMKansas: 1 hospital filed a usable price — fewer than 10, so no figureKSArkansas: 2 hospitals filed a usable price — fewer than 10, so no figureARTennessee: 6 hospitals filed a usable price — fewer than 10, so no figureTNNorth Carolina: 3 hospitals filed a usable price — fewer than 10, so no figureNCSouth Carolina: 4 hospitals filed a usable price — fewer than 10, so no figureSCOklahoma: median $340 across 12 hospitalsOK$340Louisiana: median $487 across 13 hospitalsLA$487Mississippi: no hospital in the corpus filed a usable priceMSAlabama: no hospital in the corpus filed a usable priceALGeorgia: no hospital in the corpus filed a usable priceGAHawaii: 4 hospitals filed a usable price — fewer than 10, so no figureHITexas: median $1,118 across 18 hospitalsTX$1,118Florida: 3 hospitals filed a usable price — fewer than 10, so no figureFL
Cash price by state, most expensive first. National median $753. A state needs at least 10 hospitals with a usable price to show a figure.
StateHospitalsMedianvs national20th–80th
New Jersey NJ23$3,786+403%$607 – $5,419
Wisconsin WI16$1,844+145%$1,054 – $1,844
Texas TX18$1,118+48%$950 – $1,290
California CA43$1,050+39%$1,014 – $2,010
Michigan MI10$7560%$426 – $1,844
Iowa IA14$697−7%$697 – $697
New York NY23$649−14%$649 – $687
Pennsylvania PA24$597−21%$132 – $1,227
Illinois IL17$507−33%$208 – $1,736
Louisiana LA13$487−35%$360 – $563
Oklahoma OK12$340−55%$340 – $340
Colorado CO9not enough hospitals filed a usable price
Minnesota MN9not enough hospitals filed a usable price
Oregon OR7not enough hospitals filed a usable price
Idaho ID6not enough hospitals filed a usable price
Tennessee TN6not enough hospitals filed a usable price
Ohio OH5not enough hospitals filed a usable price
Hawaii HI4not enough hospitals filed a usable price
Massachusetts MA4not enough hospitals filed a usable price
Missouri MO4not enough hospitals filed a usable price
New Hampshire NH4not enough hospitals filed a usable price
South Carolina SC4not enough hospitals filed a usable price
Washington WA4not enough hospitals filed a usable price
Florida FL3not enough hospitals filed a usable price
North Carolina NC3not enough hospitals filed a usable price
Nebraska NE3not enough hospitals filed a usable price
West Virginia WV3not enough hospitals filed a usable price
Arkansas AR2not enough hospitals filed a usable price
Arizona AZ2not enough hospitals filed a usable price
Kentucky KY2not enough hospitals filed a usable price
Vermont VT2not enough hospitals filed a usable price
Wyoming WY2not enough hospitals filed a usable price
Alaska AK1not enough hospitals filed a usable price
Kansas KS1not enough hospitals filed a usable price
Montana MT1not enough hospitals filed a usable price
Nevada NV1not enough hospitals filed a usable price
Utah UT1not enough hospitals filed a usable price

Hospitals like yours

The same distribution cut by the kind of hospital. Hospital type and ownership come from CMS; a hospital counts as part of a system when its price file is shared with at least one other hospital under the same brand. The national median is $753.

Cash price by hospital segment. A segment needs at least 20 hospitals to show a figure.
SegmentHospitalsMedian20th–80th
Hospital type
Acute care276$727$427 – $1,844
Children’s5fewer than 20 hospitals
Critical access25$1,535$529 – $1,844
Ownership
For-profit26$656$312 – $1,253
Government36$649$484 – $950
Non-profit244$783$427 – $1,844
System affiliation
Part of a system266$783$427 – $1,844
Independent40$632$439 – $937

Cash price vs list price

Median list price (chargemaster)$1,709
Median cash price$753
Cash as a share of list, median hospital56%

At the typical hospital, asking for the cash price cuts the list price by about 44%. The share is the median of each hospital’s own cash ÷ list ratio, over hospitals that filed both — not the ratio of the two medians above.

The same procedure, inpatient

207 hospitals filed a usable inpatient cash price for this code. The median is $874 and the average of the middle 60% is $1,006; most fall between $373 and $1,844.

Cash price percentiles, inpatient, across 207 hospitals. Each figure is a price a hospital filed. 10th: one in ten hospitals charges less; 25th: a quarter charge less; Median: half charge less; 75th: three quarters charge less; 90th: nine in ten charge less.
10th25thMedian75th90th
$316$427$874$1,653$2,010

The most expensive tenth of hospitals charges at least 6.4× what the cheapest tenth charges ($316 vs $2,010).

Of the 221 hospitals that filed this code inpatient, 207 gave a usable cash price; 7 carried a plausibility flag, 0 filed a number their own filing marks as not a price, 0 gave an estimate, and 7 a list price only.

How complete is this

306 of the 3,956 hospitals with a price file in our corpus (8%) filed a usable outpatient cash price for this code, and those are the hospitals every figure on this page is computed from.

What the 323 hospitals that filed this code at all gave us
Usable cash price — counted306
Cash price carrying a plausibility flag — shown on the compare tool, excluded here9
A number the filing itself marks as not a price (a placeholder, a ratio) — excluded1
An estimate rather than a filed cash price — excluded0
A list price only, no cash figure — excluded7
Hospitals that filed this code323

Sections not shown for this setting

  • Since our last snapshot: there is no earlier snapshot at least 90 days older than this one yet.

We last checked these hospitals’ price files for changes between September 4, 2026 and September 24, 2026; the figures were computed September 25, 2026 from filings loaded through September 23, 2026. The percentiles and averages use only the “counted” row.

Related procedures

Part of the Destruction of lesion of retina and choroid family.

Hospitals file this code under descriptions such as Dstrj Lesion Choroid Photodynamic Therapy.

Method

Source
The machine-readable price files every U.S. hospital is required by CMS to publish, parsed per hospital. Nothing is surveyed, sampled or modelled.
What counts
One cash (self-pay) price per hospital for this code and setting. A hospital’s own filing can rule its number out — a placeholder, a “not applicable” note, a list price standing in for cash — and our plausibility checks can flag a price far below what every other hospital files. Both kinds are disclosed above and excluded from the statistics; on the compare tool a flagged price is still shown.
Statistics
Percentiles are discrete: each is a price some hospital filed. The average is the mean of the prices between the 20th and 80th percentiles. We never publish the plain mean, the minimum or the maximum. A state needs 10 hospitals and a segment 20 to show a figure; otherwise the row shows its count and no number. Medicare is the national unadjusted OPPS rate where one exists.
Names
Procedure names on these pages are our own plain-language titles, not the AMA’s copyrighted CPT descriptors. The code is the identity.

The full rules — sources, statistics, thresholds, limitations — are on the methodology page.

Download this page’s figures: JSON · CSV. Aggregates only — the per-hospital prices are on the compare tool.

Cite: HospitalRates.com, “Light-activated drug therapy for choroid lesion, one eye (CPT 67221) — cash price report,” computed September 25, 2026. https://hospitalrates.com/procedures/cpt-67221-light-activated-drug-therapy-for-choroid-lesion-one-eye