{"procedure":{"code_type":"CPT","code":"81330","lay_name":"SMPD1 gene test for common variants","blurb":"Laboratory test that checks the SMPD1 gene for a small set of frequently seen changes associated with an inherited metabolic storage disease.","slug":"cpt-81330-smpd1-gene-test-for-common-variants","description":"SMPD1 GENE COMMON VARIANTS","name_source":"llm:claude-opus-5","name_reviewed":false,"ccs":{"code":"234","label":"Pathology","surgery_flag":"n/a"}},"settings":{"outpatient":{"setting":"outpatient","computed_at":"2026-09-25T11:55:12.319193Z","corpus_loaded_through":"2026-09-23T22:20:23.317834Z","filing_date_min":"2024-10-01","filing_date_max":"2026-09-22","checked_from":"2026-09-05T02:22:45.006185Z","checked_through":"2026-09-25T01:09:30.311445Z","n_priced_setters":3956,"n_filed":573,"n_usable":534,"n_not_usable":0,"n_labelled":32,"n_no_cash":7,"n_estimated":0,"n_states":42,"cash_p10":37.05,"cash_p20":51.7,"cash_p25":63.77,"cash_p50":133.84,"cash_p75":266.0,"cash_p80":326.75,"cash_p90":733.2,"cash_mean_trimmed":148.65,"gross_p50":239.0,"cash_to_gross_p50":0.6,"medicare_rate":null,"medicare_schedule":null,"medicare_year":null,"cash_to_medicare_p50":null,"by_state":[{"state":"AK","n":2,"p20":null,"p50":null,"p80":null},{"state":"AL","n":5,"p20":null,"p50":null,"p80":null},{"state":"AZ","n":4,"p20":null,"p50":null,"p80":null},{"state":"CA","n":29,"p20":34.61,"p50":133.84,"p80":133.84},{"state":"CO","n":5,"p20":null,"p50":null,"p80":null},{"state":"CT","n":5,"p20":null,"p50":null,"p80":null},{"state":"DE","n":3,"p20":null,"p50":null,"p80":null},{"state":"FL","n":17,"p20":76.0,"p50":80.0,"p80":105.0},{"state":"HI","n":1,"p20":null,"p50":null,"p80":null},{"state":"IA","n":12,"p20":127.86,"p50":127.86,"p80":127.86},{"state":"IL","n":25,"p20":108.5,"p50":140.0,"p80":155.0},{"state":"IN","n":28,"p20":68.14,"p50":96.91,"p80":247.29},{"state":"KS","n":5,"p20":null,"p50":null,"p80":null},{"state":"KY","n":14,"p20":99.84,"p50":330.6,"p80":1664.14},{"state":"LA","n":6,"p20":null,"p50":null,"p80":null},{"state":"MA","n":20,"p20":69.75,"p50":202.0,"p80":505.0},{"state":"MD","n":11,"p20":20.93,"p50":235.6,"p80":320.67},{"state":"ME","n":7,"p20":null,"p50":null,"p80":null},{"state":"MI","n":19,"p20":30.62,"p50":36.4,"p80":64.86},{"state":"MN","n":17,"p20":26.54,"p50":90.22,"p80":173.49},{"state":"MO","n":10,"p20":156.0,"p50":230.45,"p80":230.45},{"state":"MS","n":4,"p20":null,"p50":null,"p80":null},{"state":"NC","n":23,"p20":87.4,"p50":197.6,"p80":649.0},{"state":"ND","n":1,"p20":null,"p50":null,"p80":null},{"state":"NH","n":5,"p20":null,"p50":null,"p80":null},{"state":"NJ","n":34,"p20":47.0,"p50":51.7,"p80":1330.0},{"state":"NM","n":3,"p20":null,"p50":null,"p80":null},{"state":"NV","n":4,"p20":null,"p50":null,"p80":null},{"state":"NY","n":33,"p20":47.0,"p50":70.5,"p80":294.0},{"state":"OH","n":55,"p20":152.4,"p50":330.6,"p80":733.2},{"state":"OK","n":8,"p20":null,"p50":null,"p80":null},{"state":"OR","n":2,"p20":null,"p50":null,"p80":null},{"state":"PA","n":34,"p20":34.08,"p50":226.0,"p80":1022.56},{"state":"RI","n":1,"p20":null,"p50":null,"p80":null},{"state":"TN","n":6,"p20":null,"p50":null,"p80":null},{"state":"TX","n":31,"p20":28.5,"p50":240.0,"p80":240.0},{"state":"UT","n":2,"p20":null,"p50":null,"p80":null},{"state":"VA","n":6,"p20":null,"p50":null,"p80":null},{"state":"VT","n":1,"p20":null,"p50":null,"p80":null},{"state":"WA","n":17,"p20":45.35,"p50":72.8,"p80":72.8},{"state":"WI","n":17,"p20":135.3,"p50":160.0,"p80":188.74},{"state":"WV","n":2,"p20":null,"p50":null,"p80":null}],"by_segment":{"hospital_type":[{"key":"acute","n":466,"p20":51.7,"p50":133.84,"p80":320.67},{"key":"childrens","n":17,"p20":null,"p50":null,"p80":null},{"key":"critical_access","n":46,"p20":84.0,"p50":152.4,"p80":330.6}],"ownership":[{"key":"for_profit","n":27,"p20":52.85,"p50":95.2,"p80":160.0},{"key":"government","n":50,"p20":47.0,"p50":97.2,"p80":266.0},{"key":"nonprofit","n":452,"p20":51.7,"p50":140.0,"p80":330.6}],"affiliation":[{"key":"affiliated","n":485,"p20":51.7,"p50":133.84,"p80":327.6},{"key":"independent","n":49,"p20":54.05,"p50":118.1,"p80":202.69}]},"histogram":[{"lo":28.5,"hi":40.77,"n":36},{"lo":40.77,"hi":58.32,"n":65},{"lo":58.32,"hi":83.43,"n":63},{"lo":83.43,"hi":119.34,"n":48},{"lo":119.34,"hi":170.71,"n":83},{"lo":170.71,"hi":244.2,"n":79},{"lo":244.2,"hi":349.33,"n":52},{"lo":349.33,"hi":499.71,"n":11},{"lo":499.71,"hi":714.83,"n":19},{"lo":714.83,"hi":1022.56,"n":31}],"previous":null},"inpatient":{"setting":"inpatient","computed_at":"2026-09-25T11:55:12.319193Z","corpus_loaded_through":"2026-09-23T22:20:23.317834Z","filing_date_min":"2024-10-01","filing_date_max":"2026-09-01","checked_from":"2026-09-05T11:18:47.736875Z","checked_through":"2026-09-25T01:09:30.311445Z","n_priced_setters":3956,"n_filed":393,"n_usable":367,"n_not_usable":0,"n_labelled":18,"n_no_cash":8,"n_estimated":0,"n_states":37,"cash_p10":34.61,"cash_p20":62.4,"cash_p25":82.6,"cash_p50":152.4,"cash_p75":247.29,"cash_p80":294.0,"cash_p90":640.9,"cash_mean_trimmed":164.96,"gross_p50":239.0,"cash_to_gross_p50":0.6,"medicare_rate":null,"medicare_schedule":null,"medicare_year":null,"cash_to_medicare_p50":null,"by_state":[{"state":"AL","n":4,"p20":null,"p50":null,"p80":null},{"state":"AZ","n":3,"p20":null,"p50":null,"p80":null},{"state":"CA","n":28,"p20":34.61,"p50":133.84,"p80":133.84},{"state":"CO","n":5,"p20":null,"p50":null,"p80":null},{"state":"CT","n":1,"p20":null,"p50":null,"p80":null},{"state":"DE","n":2,"p20":null,"p50":null,"p80":null},{"state":"FL","n":5,"p20":null,"p50":null,"p80":null},{"state":"HI","n":1,"p20":null,"p50":null,"p80":null},{"state":"IA","n":11,"p20":127.86,"p50":127.86,"p80":127.86},{"state":"IL","n":15,"p20":127.86,"p50":140.0,"p80":155.0},{"state":"IN","n":12,"p20":201.2,"p50":241.49,"p80":313.47},{"state":"KY","n":7,"p20":null,"p50":null,"p80":null},{"state":"LA","n":2,"p20":null,"p50":null,"p80":null},{"state":"MA","n":20,"p20":69.75,"p50":202.0,"p80":505.0},{"state":"MD","n":3,"p20":null,"p50":null,"p80":null},{"state":"ME","n":7,"p20":null,"p50":null,"p80":null},{"state":"MI","n":15,"p20":30.62,"p50":30.62,"p80":60.48},{"state":"MN","n":17,"p20":26.54,"p50":90.22,"p80":173.49},{"state":"MO","n":9,"p20":null,"p50":null,"p80":null},{"state":"MS","n":3,"p20":null,"p50":null,"p80":null},{"state":"NC","n":6,"p20":null,"p50":null,"p80":null},{"state":"ND","n":1,"p20":null,"p50":null,"p80":null},{"state":"NH","n":5,"p20":null,"p50":null,"p80":null},{"state":"NJ","n":4,"p20":null,"p50":null,"p80":null},{"state":"NM","n":1,"p20":null,"p50":null,"p80":null},{"state":"NV","n":3,"p20":null,"p50":null,"p80":null},{"state":"NY","n":13,"p20":62.0,"p50":111.0,"p80":320.4},{"state":"OH","n":54,"p20":152.4,"p50":330.6,"p80":733.2},{"state":"OK","n":6,"p20":null,"p50":null,"p80":null},{"state":"OR","n":2,"p20":null,"p50":null,"p80":null},{"state":"PA","n":32,"p20":40.56,"p50":226.0,"p80":1022.56},{"state":"TN","n":4,"p20":null,"p50":null,"p80":null},{"state":"TX","n":27,"p20":28.5,"p50":240.0,"p80":240.0},{"state":"VA","n":5,"p20":null,"p50":null,"p80":null},{"state":"VT","n":1,"p20":null,"p50":null,"p80":null},{"state":"WA","n":16,"p20":45.35,"p50":71.4,"p80":91.2},{"state":"WI","n":17,"p20":135.3,"p50":160.0,"p80":188.74}],"by_segment":{"hospital_type":[{"key":"acute","n":321,"p20":60.48,"p50":145.6,"p80":284.5},{"key":"childrens","n":12,"p20":null,"p50":null,"p80":null},{"key":"critical_access","n":29,"p20":72.61,"p50":224.95,"p80":330.6}],"ownership":[{"key":"for_profit","n":15,"p20":null,"p50":null,"p80":null},{"key":"government","n":26,"p20":65.88,"p50":104.88,"p80":167.94},{"key":"nonprofit","n":321,"p20":69.75,"p50":158.1,"p80":313.47}],"affiliation":[{"key":"affiliated","n":345,"p20":63.77,"p50":156.0,"p80":299.54},{"key":"independent","n":22,"p20":44.78,"p50":97.2,"p80":180.8}]},"histogram":[{"lo":28.5,"hi":40.16,"n":30},{"lo":40.16,"hi":56.6,"n":23},{"lo":56.6,"hi":79.77,"n":22},{"lo":79.77,"hi":112.42,"n":35},{"lo":112.42,"hi":158.43,"n":67},{"lo":158.43,"hi":223.28,"n":49},{"lo":223.28,"hi":314.67,"n":56},{"lo":314.67,"hi":443.46,"n":28},{"lo":443.46,"hi":624.96,"n":4},{"lo":624.96,"hi":880.75,"n":20}],"previous":null}},"related":[{"code_type":"CPT","code":"88305","lay_name":"Tissue exam under microscope, moderate complexity","slug":"cpt-88305-tissue-exam-under-microscope-moderate-complexity"},{"code_type":"CPT","code":"88312","lay_name":"Special stain for germs such as bacteria or fungus","slug":"cpt-88312-special-stain-for-germs-such-as-bacteria-or-fungus"},{"code_type":"CPT","code":"88342","lay_name":"Special tissue stain for one marker, first stain","slug":"cpt-88342-special-tissue-stain-for-one-marker-first-stain"},{"code_type":"CPT","code":"88304","lay_name":"Tissue exam under microscope, low complexity","slug":"cpt-88304-tissue-exam-under-microscope-low-complexity"},{"code_type":"CPT","code":"88313","lay_name":"Special tissue stain for cell structures","slug":"cpt-88313-special-tissue-stain-for-cell-structures"},{"code_type":"CPT","code":"88307","lay_name":"Tissue exam under microscope, high complexity","slug":"cpt-88307-tissue-exam-under-microscope-high-complexity"},{"code_type":"CPT","code":"81241","lay_name":"Factor V Leiden blood clotting gene mutation test","slug":"cpt-81241-factor-v-leiden-blood-clotting-gene-mutation-test"},{"code_type":"CPT","code":"88302","lay_name":"Tissue exam under microscope, simplest level","slug":"cpt-88302-tissue-exam-under-microscope-simplest-level"},{"code_type":"CPT","code":"88184","lay_name":"Flow cytometry cell marker testing, first marker","slug":"cpt-88184-flow-cytometry-cell-marker-testing-first-marker"},{"code_type":"CPT","code":"88341","lay_name":"Special tissue stain for one more marker","slug":"cpt-88341-special-tissue-stain-for-one-more-marker"},{"code_type":"CPT","code":"88300","lay_name":"Tissue exam by eye only, no microscope","slug":"cpt-88300-tissue-exam-by-eye-only-no-microscope"},{"code_type":"CPT","code":"81240","lay_name":"Prothrombin blood clotting gene mutation test","slug":"cpt-81240-prothrombin-blood-clotting-gene-mutation-test"}]}