{"procedure":{"code_type":"CPT","code":"81259","lay_name":"Full gene sequencing of the alpha globin genes","blurb":"A laboratory test that reads the full coding sequence of both alpha globin genes, used when common deletion testing does not explain the findings.","slug":"cpt-81259-full-gene-sequencing-of-the-alpha-globin-genes","description":"HBA1/HBA2 FULL GENE SEQUENCE","name_source":"llm:claude-opus-5","name_reviewed":false,"ccs":{"code":"234","label":"Pathology","surgery_flag":"n/a"}},"settings":{"outpatient":{"setting":"outpatient","computed_at":"2026-09-25T11:55:12.319193Z","corpus_loaded_through":"2026-09-25T01:10:45.071082Z","filing_date_min":"2024-07-01","filing_date_max":"2026-09-22","checked_from":"2026-09-05T02:22:45.003818Z","checked_through":"2026-09-25T01:13:17.893132Z","n_priced_setters":3956,"n_filed":1110,"n_usable":1011,"n_not_usable":1,"n_labelled":74,"n_no_cash":23,"n_estimated":1,"n_states":50,"cash_p10":315.0,"cash_p20":450.0,"cash_p25":504.0,"cash_p50":769.95,"cash_p75":1188.0,"cash_p80":1372.0,"cash_p90":1908.75,"cash_mean_trimmed":812.03,"gross_p50":1380.83,"cash_to_gross_p50":0.6,"medicare_rate":null,"medicare_schedule":null,"medicare_year":null,"cash_to_medicare_p50":null,"by_state":[{"state":"AK","n":2,"p20":null,"p50":null,"p80":null},{"state":"AL","n":1,"p20":null,"p50":null,"p80":null},{"state":"AR","n":15,"p20":291.06,"p50":451.1,"p80":525.94},{"state":"AZ","n":13,"p20":346.55,"p50":690.0,"p80":916.8},{"state":"CA","n":30,"p20":549.0,"p50":1372.0,"p80":1372.0},{"state":"CO","n":25,"p20":310.48,"p50":474.5,"p80":756.95},{"state":"CT","n":8,"p20":null,"p50":null,"p80":null},{"state":"DE","n":5,"p20":null,"p50":null,"p80":null},{"state":"FL","n":26,"p20":293.44,"p50":367.0,"p80":2083.73},{"state":"GA","n":47,"p20":166.2,"p50":338.24,"p80":1908.75},{"state":"HI","n":5,"p20":null,"p50":null,"p80":null},{"state":"IA","n":22,"p20":576.0,"p50":576.0,"p80":987.0},{"state":"ID","n":9,"p20":null,"p50":null,"p80":null},{"state":"IL","n":44,"p20":565.0,"p50":747.6,"p80":1244.1},{"state":"IN","n":24,"p20":645.51,"p50":760.2,"p80":1228.36},{"state":"KS","n":12,"p20":604.8,"p50":937.16,"p80":5073.71},{"state":"KY","n":21,"p20":626.62,"p50":1800.0,"p80":2999.27},{"state":"LA","n":17,"p20":297.0,"p50":741.66,"p80":833.92},{"state":"MA","n":15,"p20":831.0,"p50":1035.0,"p80":1254.63},{"state":"MD","n":16,"p20":729.86,"p50":975.74,"p80":2523.69},{"state":"ME","n":3,"p20":null,"p50":null,"p80":null},{"state":"MI","n":27,"p20":799.26,"p50":828.0,"p80":1739.4},{"state":"MN","n":45,"p20":290.22,"p50":477.91,"p80":592.0},{"state":"MO","n":35,"p20":453.7,"p50":900.6,"p80":1156.0},{"state":"MS","n":6,"p20":null,"p50":null,"p80":null},{"state":"MT","n":2,"p20":null,"p50":null,"p80":null},{"state":"NC","n":20,"p20":617.18,"p50":617.18,"p80":952.56},{"state":"ND","n":5,"p20":null,"p50":null,"p80":null},{"state":"NE","n":2,"p20":null,"p50":null,"p80":null},{"state":"NH","n":8,"p20":null,"p50":null,"p80":null},{"state":"NJ","n":33,"p20":600.0,"p50":660.0,"p80":715.25},{"state":"NM","n":2,"p20":null,"p50":null,"p80":null},{"state":"NV","n":7,"p20":null,"p50":null,"p80":null},{"state":"NY","n":40,"p20":600.0,"p50":642.6,"p80":1413.29},{"state":"OH","n":69,"p20":568.8,"p50":1012.5,"p80":1307.8},{"state":"OK","n":19,"p20":459.55,"p50":733.92,"p80":1285.2},{"state":"OR","n":14,"p20":720.0,"p50":720.0,"p80":1251.25},{"state":"PA","n":31,"p20":432.0,"p50":1240.0,"p80":5424.3},{"state":"RI","n":3,"p20":null,"p50":null,"p80":null},{"state":"SC","n":17,"p20":552.0,"p50":945.1,"p80":945.1},{"state":"SD","n":6,"p20":null,"p50":null,"p80":null},{"state":"TN","n":25,"p20":235.62,"p50":755.55,"p80":769.95},{"state":"TX","n":66,"p20":450.0,"p50":787.5,"p80":1101.45},{"state":"UT","n":24,"p20":1035.62,"p50":1035.62,"p80":1218.38},{"state":"VA","n":33,"p20":230.5,"p50":769.95,"p80":1763.0},{"state":"VT","n":2,"p20":null,"p50":null,"p80":null},{"state":"WA","n":21,"p20":346.0,"p50":494.28,"p80":973.6},{"state":"WI","n":62,"p20":565.0,"p50":698.94,"p80":1909.24},{"state":"WV","n":22,"p20":827.5,"p50":827.5,"p80":1670.0},{"state":"WY","n":5,"p20":null,"p50":null,"p80":null}],"by_segment":{"hospital_type":[{"key":"acute","n":812,"p20":436.0,"p50":769.95,"p80":1372.0},{"key":"childrens","n":27,"p20":473.0,"p50":604.8,"p80":1142.3},{"key":"critical_access","n":166,"p20":455.0,"p50":799.26,"p80":1338.8}],"ownership":[{"key":"for_profit","n":62,"p20":338.24,"p50":863.62,"p80":1800.0},{"key":"government","n":129,"p20":351.99,"p50":617.18,"p80":1105.65},{"key":"nonprofit","n":814,"p20":467.5,"p50":787.5,"p80":1372.0}],"affiliation":[{"key":"affiliated","n":903,"p20":450.0,"p50":787.5,"p80":1372.0},{"key":"independent","n":108,"p20":434.28,"p50":662.0,"p80":1134.6}]},"histogram":[{"lo":230.5,"hi":293.45,"n":41},{"lo":293.45,"hi":373.6,"n":67},{"lo":373.6,"hi":475.64,"n":82},{"lo":475.64,"hi":605.55,"n":140},{"lo":605.55,"hi":770.94,"n":131},{"lo":770.94,"hi":981.51,"n":148},{"lo":981.51,"hi":1249.58,"n":128},{"lo":1249.58,"hi":1590.87,"n":67},{"lo":1590.87,"hi":2025.37,"n":73},{"lo":2025.37,"hi":2578.55,"n":39}],"previous":null},"inpatient":{"setting":"inpatient","computed_at":"2026-09-25T11:55:12.319193Z","corpus_loaded_through":"2026-09-25T01:05:50.973703Z","filing_date_min":"2024-07-01","filing_date_max":"2026-09-21","checked_from":"2026-09-05T02:23:05.982663Z","checked_through":"2026-09-25T01:13:17.893132Z","n_priced_setters":3956,"n_filed":849,"n_usable":770,"n_not_usable":0,"n_labelled":57,"n_no_cash":22,"n_estimated":0,"n_states":47,"cash_p10":310.48,"cash_p20":441.0,"cash_p25":501.2,"cash_p50":799.26,"cash_p75":1244.1,"cash_p80":1413.29,"cash_p90":1949.68,"cash_mean_trimmed":845.67,"gross_p50":1402.0,"cash_to_gross_p50":0.6,"medicare_rate":null,"medicare_schedule":null,"medicare_year":null,"cash_to_medicare_p50":null,"by_state":[{"state":"AL","n":1,"p20":null,"p50":null,"p80":null},{"state":"AR","n":5,"p20":null,"p50":null,"p80":null},{"state":"AZ","n":11,"p20":375.0,"p50":780.0,"p80":916.8},{"state":"CA","n":29,"p20":564.72,"p50":1372.0,"p80":1372.0},{"state":"CO","n":22,"p20":310.48,"p50":432.0,"p80":777.6},{"state":"CT","n":3,"p20":null,"p50":null,"p80":null},{"state":"DE","n":4,"p20":null,"p50":null,"p80":null},{"state":"FL","n":18,"p20":319.2,"p50":717.0,"p80":2100.0},{"state":"GA","n":46,"p20":166.2,"p50":338.24,"p80":1908.75},{"state":"HI","n":1,"p20":null,"p50":null,"p80":null},{"state":"IA","n":20,"p20":576.0,"p50":576.0,"p80":987.0},{"state":"ID","n":7,"p20":null,"p50":null,"p80":null},{"state":"IL","n":44,"p20":565.0,"p50":935.2,"p80":1244.1},{"state":"IN","n":9,"p20":null,"p50":null,"p80":null},{"state":"KS","n":6,"p20":null,"p50":null,"p80":null},{"state":"KY","n":13,"p20":551.32,"p50":759.24,"p80":1800.0},{"state":"LA","n":13,"p20":297.0,"p50":741.66,"p80":833.92},{"state":"MA","n":12,"p20":831.0,"p50":838.0,"p80":1218.0},{"state":"MD","n":8,"p20":null,"p50":null,"p80":null},{"state":"ME","n":3,"p20":null,"p50":null,"p80":null},{"state":"MI","n":17,"p20":799.26,"p50":799.26,"p80":1739.4},{"state":"MN","n":42,"p20":290.22,"p50":445.0,"p80":592.0},{"state":"MO","n":21,"p20":900.6,"p50":1120.2,"p80":1188.0},{"state":"MT","n":2,"p20":null,"p50":null,"p80":null},{"state":"NC","n":20,"p20":617.18,"p50":617.18,"p80":952.56},{"state":"ND","n":4,"p20":null,"p50":null,"p80":null},{"state":"NE","n":1,"p20":null,"p50":null,"p80":null},{"state":"NH","n":7,"p20":null,"p50":null,"p80":null},{"state":"NJ","n":7,"p20":null,"p50":null,"p80":null},{"state":"NM","n":1,"p20":null,"p50":null,"p80":null},{"state":"NV","n":6,"p20":null,"p50":null,"p80":null},{"state":"NY","n":17,"p20":985.2,"p50":1413.29,"p80":2536.0},{"state":"OH","n":68,"p20":726.24,"p50":1051.5,"p80":1413.6},{"state":"OK","n":7,"p20":null,"p50":null,"p80":null},{"state":"OR","n":7,"p20":null,"p50":null,"p80":null},{"state":"PA","n":27,"p20":1292.07,"p50":1686.72,"p80":5455.59},{"state":"SC","n":17,"p20":552.0,"p50":945.1,"p80":945.1},{"state":"SD","n":2,"p20":null,"p50":null,"p80":null},{"state":"TN","n":23,"p20":235.62,"p50":755.55,"p80":769.95},{"state":"TX","n":61,"p20":450.0,"p50":787.5,"p80":1101.45},{"state":"UT","n":22,"p20":1035.62,"p50":1035.62,"p80":1218.38},{"state":"VA","n":32,"p20":230.5,"p50":755.55,"p80":1763.0},{"state":"VT","n":1,"p20":null,"p50":null,"p80":null},{"state":"WA","n":21,"p20":432.4,"p50":494.28,"p80":973.6},{"state":"WI","n":54,"p20":565.0,"p50":698.25,"p80":2578.55},{"state":"WV","n":5,"p20":null,"p50":null,"p80":null},{"state":"WY","n":3,"p20":null,"p50":null,"p80":null}],"by_segment":{"hospital_type":[{"key":"acute","n":634,"p20":432.0,"p50":797.04,"p80":1413.29},{"key":"childrens","n":20,"p20":473.0,"p50":656.25,"p80":1142.3},{"key":"critical_access","n":110,"p20":562.38,"p50":935.2,"p80":1786.4}],"ownership":[{"key":"for_profit","n":50,"p20":305.93,"p50":574.61,"p80":1800.0},{"key":"government","n":86,"p20":338.24,"p50":617.18,"p80":1270.08},{"key":"nonprofit","n":628,"p20":467.5,"p50":868.8,"p80":1413.29}],"affiliation":[{"key":"affiliated","n":701,"p20":450.0,"p50":840.66,"p80":1413.6},{"key":"independent","n":69,"p20":360.6,"p50":592.0,"p80":1142.3}]},"histogram":[{"lo":230.5,"hi":293.45,"n":32},{"lo":293.45,"hi":373.6,"n":53},{"lo":373.6,"hi":475.64,"n":62},{"lo":475.64,"hi":605.55,"n":91},{"lo":605.55,"hi":770.94,"n":81},{"lo":770.94,"hi":981.51,"n":103},{"lo":981.51,"hi":1249.58,"n":118},{"lo":1249.58,"hi":1590.87,"n":56},{"lo":1590.87,"hi":2025.37,"n":68},{"lo":2025.37,"hi":2578.55,"n":33}],"previous":null}},"related":[{"code_type":"CPT","code":"88305","lay_name":"Tissue exam under microscope, moderate complexity","slug":"cpt-88305-tissue-exam-under-microscope-moderate-complexity"},{"code_type":"CPT","code":"88312","lay_name":"Special stain for germs such as bacteria or fungus","slug":"cpt-88312-special-stain-for-germs-such-as-bacteria-or-fungus"},{"code_type":"CPT","code":"88342","lay_name":"Special tissue stain for one marker, first stain","slug":"cpt-88342-special-tissue-stain-for-one-marker-first-stain"},{"code_type":"CPT","code":"88304","lay_name":"Tissue exam under microscope, low complexity","slug":"cpt-88304-tissue-exam-under-microscope-low-complexity"},{"code_type":"CPT","code":"88313","lay_name":"Special tissue stain for cell structures","slug":"cpt-88313-special-tissue-stain-for-cell-structures"},{"code_type":"CPT","code":"88307","lay_name":"Tissue exam under microscope, high complexity","slug":"cpt-88307-tissue-exam-under-microscope-high-complexity"},{"code_type":"CPT","code":"81241","lay_name":"Factor V Leiden blood clotting gene mutation test","slug":"cpt-81241-factor-v-leiden-blood-clotting-gene-mutation-test"},{"code_type":"CPT","code":"88302","lay_name":"Tissue exam under microscope, simplest level","slug":"cpt-88302-tissue-exam-under-microscope-simplest-level"},{"code_type":"CPT","code":"88184","lay_name":"Flow cytometry cell marker testing, first marker","slug":"cpt-88184-flow-cytometry-cell-marker-testing-first-marker"},{"code_type":"CPT","code":"88341","lay_name":"Special tissue stain for one more marker","slug":"cpt-88341-special-tissue-stain-for-one-more-marker"},{"code_type":"CPT","code":"88300","lay_name":"Tissue exam by eye only, no microscope","slug":"cpt-88300-tissue-exam-by-eye-only-no-microscope"},{"code_type":"CPT","code":"81240","lay_name":"Prothrombin blood clotting gene mutation test","slug":"cpt-81240-prothrombin-blood-clotting-gene-mutation-test"}]}