{"procedure":{"code_type":"CPT","code":"81253","lay_name":"Connexin 26 gene test for a known family variant","blurb":"A laboratory test that checks a sample only for a specific GJB2 gene change already identified in a relative, rather than sequencing the whole gene.","slug":"cpt-81253-connexin-26-gene-test-for-a-known-family-variant","description":"GJB2 GENE KNOWN FAM VARIANTS","name_source":"llm:claude-opus-5","name_reviewed":false,"ccs":{"code":"234","label":"Pathology","surgery_flag":"n/a"}},"settings":{"outpatient":{"setting":"outpatient","computed_at":"2026-09-25T11:55:12.319193Z","corpus_loaded_through":"2026-09-23T18:10:27.249802Z","filing_date_min":"2025-10-14","filing_date_max":"2026-09-22","checked_from":"2026-09-05T11:18:47.736875Z","checked_through":"2026-09-25T01:09:27.151989Z","n_priced_setters":3956,"n_filed":244,"n_usable":229,"n_not_usable":1,"n_labelled":4,"n_no_cash":10,"n_estimated":0,"n_states":34,"cash_p10":61.52,"cash_p20":73.82,"cash_p25":73.82,"cash_p50":141.12,"cash_p75":378.24,"cash_p80":442.0,"cash_p90":734.02,"cash_mean_trimmed":192.98,"gross_p50":395.0,"cash_to_gross_p50":0.56,"medicare_rate":null,"medicare_schedule":null,"medicare_year":null,"cash_to_medicare_p50":null,"by_state":[{"state":"AL","n":1,"p20":null,"p50":null,"p80":null},{"state":"AR","n":1,"p20":null,"p50":null,"p80":null},{"state":"AZ","n":2,"p20":null,"p50":null,"p80":null},{"state":"CA","n":21,"p20":141.12,"p50":141.12,"p80":141.12},{"state":"CO","n":2,"p20":null,"p50":null,"p80":null},{"state":"CT","n":4,"p20":null,"p50":null,"p80":null},{"state":"DE","n":1,"p20":null,"p50":null,"p80":null},{"state":"FL","n":2,"p20":null,"p50":null,"p80":null},{"state":"GA","n":5,"p20":null,"p50":null,"p80":null},{"state":"ID","n":1,"p20":null,"p50":null,"p80":null},{"state":"IL","n":12,"p20":99.0,"p50":129.5,"p80":129.5},{"state":"IN","n":12,"p20":78.47,"p50":89.14,"p80":120.48},{"state":"KS","n":1,"p20":null,"p50":null,"p80":null},{"state":"KY","n":2,"p20":null,"p50":null,"p80":null},{"state":"LA","n":3,"p20":null,"p50":null,"p80":null},{"state":"MA","n":3,"p20":null,"p50":null,"p80":null},{"state":"MD","n":1,"p20":null,"p50":null,"p80":null},{"state":"MI","n":13,"p20":84.9,"p50":442.0,"p80":442.0},{"state":"MN","n":11,"p20":375.0,"p50":440.0,"p80":440.0},{"state":"MO","n":2,"p20":null,"p50":null,"p80":null},{"state":"MS","n":2,"p20":null,"p50":null,"p80":null},{"state":"NC","n":1,"p20":null,"p50":null,"p80":null},{"state":"NJ","n":22,"p20":61.52,"p50":67.67,"p80":67.67},{"state":"NV","n":2,"p20":null,"p50":null,"p80":null},{"state":"NY","n":16,"p20":61.52,"p50":61.52,"p80":73.82},{"state":"OH","n":18,"p20":633.1,"p50":820.3,"p80":827.45},{"state":"OK","n":3,"p20":null,"p50":null,"p80":null},{"state":"OR","n":3,"p20":null,"p50":null,"p80":null},{"state":"PA","n":15,"p20":308.4,"p50":767.38,"p80":898.8},{"state":"TN","n":1,"p20":null,"p50":null,"p80":null},{"state":"TX","n":16,"p20":73.82,"p50":73.82,"p80":73.82},{"state":"VA","n":5,"p20":null,"p50":null,"p80":null},{"state":"WA","n":13,"p20":92.8,"p50":98.4,"p80":106.4},{"state":"WI","n":12,"p20":83.6,"p50":450.0,"p80":450.0}],"by_segment":{"hospital_type":[{"key":"acute","n":185,"p20":67.67,"p50":129.5,"p80":335.0},{"key":"childrens","n":13,"p20":null,"p50":null,"p80":null},{"key":"critical_access","n":29,"p20":102.8,"p50":375.0,"p80":450.0}],"ownership":[{"key":"for_profit","n":9,"p20":null,"p50":null,"p80":null},{"key":"government","n":27,"p20":61.52,"p50":102.8,"p80":334.88},{"key":"nonprofit","n":191,"p20":73.82,"p50":141.12,"p80":442.0}],"affiliation":[{"key":"affiliated","n":204,"p20":73.82,"p50":131.78,"p80":442.0},{"key":"independent","n":25,"p20":75.6,"p50":220.0,"p80":351.5}]},"histogram":[{"lo":61.52,"hi":79.78,"n":58},{"lo":79.78,"hi":103.46,"n":33},{"lo":103.46,"hi":134.16,"n":15},{"lo":134.16,"hi":173.98,"n":24},{"lo":173.98,"hi":225.62,"n":9},{"lo":225.62,"hi":292.58,"n":8},{"lo":292.58,"hi":379.42,"n":21},{"lo":379.42,"hi":492.04,"n":26},{"lo":492.04,"hi":638.07,"n":5},{"lo":638.07,"hi":827.45,"n":17}],"previous":null},"inpatient":{"setting":"inpatient","computed_at":"2026-09-25T11:55:12.319193Z","corpus_loaded_through":"2026-09-23T18:10:27.249802Z","filing_date_min":"2025-10-14","filing_date_max":"2026-09-15","checked_from":"2026-09-05T13:11:36.664187Z","checked_through":"2026-09-25T01:09:27.151989Z","n_priced_setters":3956,"n_filed":156,"n_usable":144,"n_not_usable":0,"n_labelled":2,"n_no_cash":10,"n_estimated":0,"n_states":25,"cash_p10":73.82,"cash_p20":98.4,"cash_p25":116.0,"cash_p50":300.5,"cash_p75":450.0,"cash_p80":577.32,"cash_p90":827.45,"cash_mean_trimmed":282.78,"gross_p50":485.93,"cash_to_gross_p50":0.6,"medicare_rate":null,"medicare_schedule":null,"medicare_year":null,"cash_to_medicare_p50":null,"by_state":[{"state":"AZ","n":1,"p20":null,"p50":null,"p80":null},{"state":"CA","n":20,"p20":141.12,"p50":141.12,"p80":141.12},{"state":"CO","n":2,"p20":null,"p50":null,"p80":null},{"state":"DE","n":1,"p20":null,"p50":null,"p80":null},{"state":"FL","n":1,"p20":null,"p50":null,"p80":null},{"state":"GA","n":2,"p20":null,"p50":null,"p80":null},{"state":"ID","n":1,"p20":null,"p50":null,"p80":null},{"state":"IL","n":2,"p20":null,"p50":null,"p80":null},{"state":"KS","n":1,"p20":null,"p50":null,"p80":null},{"state":"KY","n":2,"p20":null,"p50":null,"p80":null},{"state":"MA","n":3,"p20":null,"p50":null,"p80":null},{"state":"MD","n":1,"p20":null,"p50":null,"p80":null},{"state":"MI","n":9,"p20":null,"p50":null,"p80":null},{"state":"MN","n":11,"p20":375.0,"p50":440.0,"p80":440.0},{"state":"MO","n":2,"p20":null,"p50":null,"p80":null},{"state":"NJ","n":1,"p20":null,"p50":null,"p80":null},{"state":"NV","n":1,"p20":null,"p50":null,"p80":null},{"state":"NY","n":3,"p20":null,"p50":null,"p80":null},{"state":"OH","n":18,"p20":633.1,"p50":820.3,"p80":827.45},{"state":"OR","n":2,"p20":null,"p50":null,"p80":null},{"state":"PA","n":14,"p20":633.93,"p50":767.38,"p80":900.84},{"state":"TX","n":16,"p20":73.82,"p50":73.82,"p80":73.82},{"state":"VA","n":5,"p20":null,"p50":null,"p80":null},{"state":"WA","n":13,"p20":98.4,"p50":116.0,"p80":116.0},{"state":"WI","n":12,"p20":83.6,"p50":450.0,"p80":450.0}],"by_segment":{"hospital_type":[{"key":"acute","n":113,"p20":93.33,"p50":185.0,"p80":633.1},{"key":"childrens","n":11,"p20":null,"p50":null,"p80":null},{"key":"critical_access","n":18,"p20":null,"p50":null,"p80":null}],"ownership":[{"key":"for_profit","n":4,"p20":null,"p50":null,"p80":null},{"key":"government","n":11,"p20":null,"p50":null,"p80":null},{"key":"nonprofit","n":127,"p20":98.4,"p50":294.38,"p80":577.32}],"affiliation":[{"key":"affiliated","n":130,"p20":95.9,"p50":288.6,"p80":633.1},{"key":"independent","n":14,"p20":null,"p50":null,"p80":null}]},"histogram":[{"lo":73.82,"hi":94.45,"n":22},{"lo":94.45,"hi":120.83,"n":13},{"lo":120.83,"hi":154.6,"n":20},{"lo":154.6,"hi":197.79,"n":3},{"lo":197.79,"hi":253.06,"n":7},{"lo":253.06,"hi":323.76,"n":12},{"lo":323.76,"hi":414.22,"n":11},{"lo":414.22,"hi":529.96,"n":23},{"lo":529.96,"hi":678.03,"n":5},{"lo":678.03,"hi":867.48,"n":18}],"previous":null}},"related":[{"code_type":"CPT","code":"88305","lay_name":"Tissue exam under microscope, moderate complexity","slug":"cpt-88305-tissue-exam-under-microscope-moderate-complexity"},{"code_type":"CPT","code":"88312","lay_name":"Special stain for germs such as bacteria or fungus","slug":"cpt-88312-special-stain-for-germs-such-as-bacteria-or-fungus"},{"code_type":"CPT","code":"88342","lay_name":"Special tissue stain for one marker, first stain","slug":"cpt-88342-special-tissue-stain-for-one-marker-first-stain"},{"code_type":"CPT","code":"88304","lay_name":"Tissue exam under microscope, low complexity","slug":"cpt-88304-tissue-exam-under-microscope-low-complexity"},{"code_type":"CPT","code":"88313","lay_name":"Special tissue stain for cell structures","slug":"cpt-88313-special-tissue-stain-for-cell-structures"},{"code_type":"CPT","code":"88307","lay_name":"Tissue exam under microscope, high complexity","slug":"cpt-88307-tissue-exam-under-microscope-high-complexity"},{"code_type":"CPT","code":"81241","lay_name":"Factor V Leiden blood clotting gene mutation test","slug":"cpt-81241-factor-v-leiden-blood-clotting-gene-mutation-test"},{"code_type":"CPT","code":"88302","lay_name":"Tissue exam under microscope, simplest level","slug":"cpt-88302-tissue-exam-under-microscope-simplest-level"},{"code_type":"CPT","code":"88184","lay_name":"Flow cytometry cell marker testing, first marker","slug":"cpt-88184-flow-cytometry-cell-marker-testing-first-marker"},{"code_type":"CPT","code":"88341","lay_name":"Special tissue stain for one more marker","slug":"cpt-88341-special-tissue-stain-for-one-more-marker"},{"code_type":"CPT","code":"88300","lay_name":"Tissue exam by eye only, no microscope","slug":"cpt-88300-tissue-exam-by-eye-only-no-microscope"},{"code_type":"CPT","code":"81240","lay_name":"Prothrombin blood clotting gene mutation test","slug":"cpt-81240-prothrombin-blood-clotting-gene-mutation-test"}]}