{"procedure":{"code_type":"CPT","code":"81231","lay_name":"CYP3A5 drug-processing gene test, common variants","blurb":"A genetic test of the CYP3A5 gene that checks for the common variants affecting how the body breaks down certain medicines.","slug":"cpt-81231-cyp3a5-drug-processing-gene-test-common-variants","description":"Hc Cyp3A5 Gene Common Variants","name_source":"llm:claude-opus-5","name_reviewed":false,"ccs":{"code":"234","label":"Pathology","surgery_flag":"n/a"}},"settings":{"outpatient":{"setting":"outpatient","computed_at":"2026-09-25T11:55:12.319193Z","corpus_loaded_through":"2026-09-25T01:05:50.973703Z","filing_date_min":"2024-12-02","filing_date_max":"2026-09-22","checked_from":"2026-09-05T10:45:50.833230Z","checked_through":"2026-09-25T01:09:30.311445Z","n_priced_setters":3956,"n_filed":653,"n_usable":577,"n_not_usable":1,"n_labelled":55,"n_no_cash":20,"n_estimated":0,"n_states":45,"cash_p10":76.81,"cash_p20":121.5,"cash_p25":142.2,"cash_p50":237.9,"cash_p75":500.25,"cash_p80":536.9,"cash_p90":783.9,"cash_mean_trimmed":265.95,"gross_p50":524.0,"cash_to_gross_p50":0.6,"medicare_rate":null,"medicare_schedule":null,"medicare_year":null,"cash_to_medicare_p50":null,"by_state":[{"state":"AK","n":2,"p20":null,"p50":null,"p80":null},{"state":"AL","n":3,"p20":null,"p50":null,"p80":null},{"state":"AR","n":4,"p20":null,"p50":null,"p80":null},{"state":"AZ","n":6,"p20":null,"p50":null,"p80":null},{"state":"CA","n":27,"p20":122.5,"p50":1209.6,"p80":1209.6},{"state":"CO","n":9,"p20":null,"p50":null,"p80":null},{"state":"CT","n":6,"p20":null,"p50":null,"p80":null},{"state":"DE","n":1,"p20":null,"p50":null,"p80":null},{"state":"FL","n":16,"p20":139.7,"p50":142.2,"p80":174.81},{"state":"GA","n":18,"p20":34.5,"p50":245.31,"p80":245.31},{"state":"HI","n":3,"p20":null,"p50":null,"p80":null},{"state":"IA","n":14,"p20":167.82,"p50":167.82,"p80":167.82},{"state":"ID","n":1,"p20":null,"p50":null,"p80":null},{"state":"IL","n":32,"p20":167.82,"p50":306.6,"p80":420.0},{"state":"IN","n":28,"p20":130.61,"p50":218.38,"p80":276.57},{"state":"KS","n":1,"p20":null,"p50":null,"p80":null},{"state":"KY","n":14,"p20":153.0,"p50":289.8,"p80":534.89},{"state":"LA","n":4,"p20":null,"p50":null,"p80":null},{"state":"MA","n":6,"p20":null,"p50":null,"p80":null},{"state":"MD","n":13,"p20":62.8,"p50":1102.96,"p80":1504.19},{"state":"MI","n":17,"p20":172.25,"p50":241.24,"p80":270.0},{"state":"MN","n":17,"p20":446.08,"p50":528.0,"p80":674.86},{"state":"MO","n":7,"p20":null,"p50":null,"p80":null},{"state":"MS","n":11,"p20":136.73,"p50":213.5,"p80":239.28},{"state":"NC","n":2,"p20":null,"p50":null,"p80":null},{"state":"ND","n":4,"p20":null,"p50":null,"p80":null},{"state":"NE","n":3,"p20":null,"p50":null,"p80":null},{"state":"NJ","n":24,"p20":174.81,"p50":192.29,"p80":192.29},{"state":"NM","n":2,"p20":null,"p50":null,"p80":null},{"state":"NV","n":6,"p20":null,"p50":null,"p80":null},{"state":"NY","n":26,"p20":174.81,"p50":307.0,"p80":506.79},{"state":"OH","n":68,"p20":121.5,"p50":481.2,"p80":1036.75},{"state":"OK","n":2,"p20":null,"p50":null,"p80":null},{"state":"OR","n":5,"p20":null,"p50":null,"p80":null},{"state":"PA","n":24,"p20":116.61,"p50":174.0,"p80":376.36},{"state":"RI","n":1,"p20":null,"p50":null,"p80":null},{"state":"SC","n":18,"p20":146.25,"p50":146.25,"p80":597.0},{"state":"TN","n":6,"p20":null,"p50":null,"p80":null},{"state":"TX","n":53,"p20":37.8,"p50":72.0,"p80":155.84},{"state":"UT","n":1,"p20":null,"p50":null,"p80":null},{"state":"VA","n":24,"p20":261.0,"p50":262.0,"p80":524.4},{"state":"WA","n":9,"p20":null,"p50":null,"p80":null},{"state":"WI","n":33,"p20":338.05,"p50":540.0,"p80":549.25},{"state":"WV","n":2,"p20":null,"p50":null,"p80":null},{"state":"WY","n":4,"p20":null,"p50":null,"p80":null}],"by_segment":{"hospital_type":[{"key":"acute","n":459,"p20":121.5,"p50":207.02,"p80":534.89},{"key":"childrens","n":14,"p20":null,"p50":null,"p80":null},{"key":"critical_access","n":101,"p20":155.84,"p50":289.8,"p80":540.0}],"ownership":[{"key":"for_profit","n":36,"p20":37.8,"p50":174.0,"p80":347.2},{"key":"government","n":69,"p20":136.73,"p50":191.43,"p80":377.47},{"key":"nonprofit","n":469,"p20":123.12,"p50":241.24,"p80":540.0}],"affiliation":[{"key":"affiliated","n":519,"p20":126.1,"p50":241.24,"p80":540.0},{"key":"independent","n":58,"p20":83.0,"p50":192.5,"p80":338.05}]},"histogram":[{"lo":37.8,"hi":53.46,"n":19},{"lo":53.46,"hi":75.6,"n":19},{"lo":75.6,"hi":106.91,"n":28},{"lo":106.91,"hi":151.2,"n":88},{"lo":151.2,"hi":213.83,"n":100},{"lo":213.83,"hi":302.4,"n":91},{"lo":302.4,"hi":427.66,"n":50},{"lo":427.66,"hi":604.8,"n":88},{"lo":604.8,"hi":855.32,"n":26},{"lo":855.32,"hi":1209.6,"n":37}],"previous":null},"inpatient":{"setting":"inpatient","computed_at":"2026-09-25T11:55:12.319193Z","corpus_loaded_through":"2026-09-25T01:05:50.973703Z","filing_date_min":"2024-12-02","filing_date_max":"2026-09-22","checked_from":"2026-09-05T11:18:47.736875Z","checked_through":"2026-09-25T01:09:30.311445Z","n_priced_setters":3956,"n_filed":467,"n_usable":411,"n_not_usable":0,"n_labelled":37,"n_no_cash":19,"n_estimated":0,"n_states":39,"cash_p10":72.0,"cash_p20":120.0,"cash_p25":123.12,"cash_p50":252.6,"cash_p75":529.2,"cash_p80":549.25,"cash_p90":783.9,"cash_mean_trimmed":293.86,"gross_p50":524.0,"cash_to_gross_p50":0.6,"medicare_rate":null,"medicare_schedule":null,"medicare_year":null,"cash_to_medicare_p50":null,"by_state":[{"state":"AL","n":1,"p20":null,"p50":null,"p80":null},{"state":"AR","n":1,"p20":null,"p50":null,"p80":null},{"state":"AZ","n":5,"p20":null,"p50":null,"p80":null},{"state":"CA","n":22,"p20":1209.6,"p50":1209.6,"p80":1209.6},{"state":"CO","n":7,"p20":null,"p50":null,"p80":null},{"state":"CT","n":1,"p20":null,"p50":null,"p80":null},{"state":"DE","n":1,"p20":null,"p50":null,"p80":null},{"state":"FL","n":3,"p20":null,"p50":null,"p80":null},{"state":"GA","n":17,"p20":34.5,"p50":245.31,"p80":245.31},{"state":"HI","n":1,"p20":null,"p50":null,"p80":null},{"state":"IA","n":12,"p20":167.82,"p50":167.82,"p80":167.82},{"state":"ID","n":1,"p20":null,"p50":null,"p80":null},{"state":"IL","n":20,"p20":138.6,"p50":236.88,"p80":424.0},{"state":"IN","n":15,"p20":97.13,"p50":131.9,"p80":205.8},{"state":"KY","n":4,"p20":null,"p50":null,"p80":null},{"state":"LA","n":2,"p20":null,"p50":null,"p80":null},{"state":"MA","n":6,"p20":null,"p50":null,"p80":null},{"state":"MD","n":6,"p20":null,"p50":null,"p80":null},{"state":"MI","n":7,"p20":null,"p50":null,"p80":null},{"state":"MN","n":17,"p20":446.08,"p50":528.0,"p80":674.86},{"state":"MO","n":7,"p20":null,"p50":null,"p80":null},{"state":"MS","n":6,"p20":null,"p50":null,"p80":null},{"state":"NC","n":2,"p20":null,"p50":null,"p80":null},{"state":"ND","n":4,"p20":null,"p50":null,"p80":null},{"state":"NE","n":1,"p20":null,"p50":null,"p80":null},{"state":"NJ","n":1,"p20":null,"p50":null,"p80":null},{"state":"NM","n":1,"p20":null,"p50":null,"p80":null},{"state":"NV","n":4,"p20":null,"p50":null,"p80":null},{"state":"NY","n":12,"p20":307.0,"p50":411.77,"p80":761.0},{"state":"OH","n":68,"p20":121.5,"p50":481.2,"p80":1036.75},{"state":"PA","n":20,"p20":117.68,"p50":157.01,"p80":376.36},{"state":"SC","n":18,"p20":146.25,"p50":146.25,"p80":597.0},{"state":"TN","n":5,"p20":null,"p50":null,"p80":null},{"state":"TX","n":50,"p20":37.8,"p50":72.0,"p80":155.84},{"state":"VA","n":23,"p20":261.0,"p50":262.0,"p80":524.4},{"state":"WA","n":8,"p20":null,"p50":null,"p80":null},{"state":"WI","n":26,"p20":189.34,"p50":540.0,"p80":549.25},{"state":"WV","n":2,"p20":null,"p50":null,"p80":null},{"state":"WY","n":4,"p20":null,"p50":null,"p80":null}],"by_segment":{"hospital_type":[{"key":"acute","n":330,"p20":114.07,"p50":240.4,"p80":540.0},{"key":"childrens","n":11,"p20":null,"p50":null,"p80":null},{"key":"critical_access","n":67,"p20":155.84,"p50":377.47,"p80":549.25}],"ownership":[{"key":"for_profit","n":22,"p20":37.8,"p50":103.8,"p80":525.0},{"key":"government","n":44,"p20":116.81,"p50":245.31,"p80":500.25},{"key":"nonprofit","n":342,"p20":120.0,"p50":261.0,"p80":549.25}],"affiliation":[{"key":"affiliated","n":375,"p20":120.0,"p50":261.0,"p80":549.25},{"key":"independent","n":36,"p20":83.0,"p50":192.5,"p80":338.05}]},"histogram":[{"lo":37.8,"hi":53.46,"n":17},{"lo":53.46,"hi":75.6,"n":18},{"lo":75.6,"hi":106.91,"n":23},{"lo":106.91,"hi":151.2,"n":66},{"lo":151.2,"hi":213.83,"n":41},{"lo":213.83,"hi":302.4,"n":65},{"lo":302.4,"hi":427.66,"n":33},{"lo":427.66,"hi":604.8,"n":71},{"lo":604.8,"hi":855.32,"n":24},{"lo":855.32,"hi":1209.6,"n":33}],"previous":null}},"related":[{"code_type":"CPT","code":"88305","lay_name":"Tissue exam under microscope, moderate complexity","slug":"cpt-88305-tissue-exam-under-microscope-moderate-complexity"},{"code_type":"CPT","code":"88312","lay_name":"Special stain for germs such as bacteria or fungus","slug":"cpt-88312-special-stain-for-germs-such-as-bacteria-or-fungus"},{"code_type":"CPT","code":"88342","lay_name":"Special tissue stain for one marker, first stain","slug":"cpt-88342-special-tissue-stain-for-one-marker-first-stain"},{"code_type":"CPT","code":"88304","lay_name":"Tissue exam under microscope, low complexity","slug":"cpt-88304-tissue-exam-under-microscope-low-complexity"},{"code_type":"CPT","code":"88313","lay_name":"Special tissue stain for cell structures","slug":"cpt-88313-special-tissue-stain-for-cell-structures"},{"code_type":"CPT","code":"88307","lay_name":"Tissue exam under microscope, high complexity","slug":"cpt-88307-tissue-exam-under-microscope-high-complexity"},{"code_type":"CPT","code":"81241","lay_name":"Factor V Leiden blood clotting gene mutation test","slug":"cpt-81241-factor-v-leiden-blood-clotting-gene-mutation-test"},{"code_type":"CPT","code":"88302","lay_name":"Tissue exam under microscope, simplest level","slug":"cpt-88302-tissue-exam-under-microscope-simplest-level"},{"code_type":"CPT","code":"88184","lay_name":"Flow cytometry cell marker testing, first marker","slug":"cpt-88184-flow-cytometry-cell-marker-testing-first-marker"},{"code_type":"CPT","code":"88341","lay_name":"Special tissue stain for one more marker","slug":"cpt-88341-special-tissue-stain-for-one-more-marker"},{"code_type":"CPT","code":"88300","lay_name":"Tissue exam by eye only, no microscope","slug":"cpt-88300-tissue-exam-by-eye-only-no-microscope"},{"code_type":"CPT","code":"81240","lay_name":"Prothrombin blood clotting gene mutation test","slug":"cpt-81240-prothrombin-blood-clotting-gene-mutation-test"}]}